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Draft Genome Sequences of Antibiotic-Resistant Commensal Escherichia coli
2014
Genome Announcements
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Antimicrobial resistance is a significant public health issue. We report here the draft genome sequences of three drug-resistant strains of commensal Escherichia coli isolated from a single healthy college student. Each strain has a distinct genome, but two of the three contain an identical large plasmid with multiple resistance genes.
doi:10.1128/genomea.00873-14
pmid:25477397
pmcid:PMC4256178
fatcat:dcy2ydlbbna5fnlisairmyytma
Fixing reference errors efficiently improves sequencing results
[article]
2022
bioRxiv
pre-print
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C) The eight pan genome samples chosen from 1KGP consists of African, American and Asian samples. ...
C) SNV and INDEL calling is improved over the mapping to the GRCh38 reference across six genes that are covered in CMRG benchmarking. ...
doi:10.1101/2022.07.18.500506
fatcat:jbjayg4fgbhcxmevfkswt2sasu
Multi-omic profiling of pituitary thyrotropic cells and progenitors
2021
BMC Biology
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The quality of the reads was checked using FastQC, aligned to the mm9 genome, and had its peaks called using the Parker lab's Snakemake pipeline [85] . ...
Stephen Liebhaber and grown as described [31] .
Cloning The DNA prepared for the plasmids used in the transfection experiments and transgenic mice was amplified from TαT1 DNA. ...
doi:10.1186/s12915-021-01009-0
pmid:33858413
pmcid:PMC8051135
fatcat:yvei7u33ujgrnieauv2v75k6xi
Genomic annotation of disease-associated variants reveals shared functional contexts
2019
Diabetologia
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Acknowledgements We thank members of the Kitzman and Parker laboratories, and associated collaborators, for invaluable discussions. ...
Most SNPs occur in noncoding regions, where chromatin state analyses (c) help identify locations of tissue-specific regulatory regions. ...
In this example, the blue 'C' allele disrupts the red motif and is associated with decreased expression of the hypothetical target 'gene X'. ...
doi:10.1007/s00125-019-4823-3
pmid:30756131
pmcid:PMC6451673
fatcat:qyltvwajnbf5rkzu32o75yhwba
Nitrate-Nitrogen, Land Use/Land Cover, and Soil Drainage Associations at Multiple Spatial Scales
2009
Journal of Environmental Quality
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Th e mean temperature is 11.1°C, with August being the warmest month (19°C) and January being the coolest (4.1°C). ...
0.64 b
20 m
-0.93 ab
-0.84 a
0.80 c
0.64 b
10 m
-0.93 ab
-0.84 a
0.79 c
0.63 b
† Hotelling-Williams test used to identify signifi cant diff erences (p < 0.05)
between two dependent correlations ...
doi:10.2134/jeq2008.0099
pmid:19465723
fatcat:ty5is4zkdjdyxdtpkyb3fqmrju
pylj: A teaching tool for classical atomistic simulation
2018
Journal of Open Source Education
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Mechanical properties of mesoporous ceria nanoarchitectures
2014
Physical Chemistry, Chemical Physics - PCCP
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exp Àr ij r À Cr ij À6 ; the first term represents the Coulombic interaction between ion i of charge Q i and ion j of charge Q j , which are a distance r ij apart. ...
Finally, the systems are crystallised to facilitate the models for nanoporous ceria with cubic, (j), or hexagonal, (o), array of 1D pores. ...
doi:10.1039/c4cp03526g
pmid:25322448
fatcat:4kjdk6zgu5eljmzibeh2fpsmvq
Engineering mesophase stability and structure via incorporation of cyclic terminal groups
2022
Journal of Materials Chemistry C
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Compound 2 was obtained via the metallophotoredox C-C coupling 19 of 4-(3-bromopropoxy)-4 0 -cyanobiphenyl with cyclobutanecarboxylic acid. ...
The structures of the phases were also assessed using pairwise correlation functions 39 of vectors between the C 4 and C 4 0 biphenyl atoms on all of the molecules, as shown in Fig. 8 . ...
doi:10.1039/d1tc05954h
fatcat:r4qib4lb2fesnjdqmfoxeqkmpy
Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding
2008
Protein Science
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j<I>j, where I i is the intensity for the ith measurement of an equivalent reflection with indices h,k,l. c R cryst ¼ SkF obs j -jF calc k/SjF obs j, where F obs and F calc are the observed and calculated ...
Citrate binds to a pocket in the B/C barrel of AAT This work indicated that citrate may exert its protective effects on AAT via binding to specific sites within the B/ C barrel of AAT. ...
doi:10.1110/ps.037234.108
pmid:18780818
pmcid:PMC2590919
fatcat:aprtwqpuabg4pjr5gpx2gjzeqy
Subunit-Specific Association of Protein Kinase C and the Receptor for Activated C Kinase with GABA Type A Receptors
1999
Journal of Neuroscience
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The receptor for activated C kinase (RACK-1) was found also to bind to the 1 subunit intracellular domain, but PKC binding appeared to be independent of this protein. ...
Here we show that protein kinase C-II (PKC-II) is capable of directly binding to the intracellular domain of the receptor 1 and 3 subunits, but not to those of the ␣1 or ␥2 subunits. ...
Brandon et al. • Subunit-Specific Association of Protein Kinase C J. Neurosci., November 1, 1999, 19(21):9228-9234 9229
J. ...
doi:10.1523/jneurosci.19-21-09228.1999
pmid:10531426
fatcat:bar2d4t46jdzvckxi2x5vmqe5m
Condensation of free volume in structures of nematic and hexatic liquid crystals
2018
Figshare
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All materials exhibit nematic mesophases, with additional smectic (Sm) C, hexatic B and SmI phases for certain homologues. ...
A B C D Angle/˚
A
B
C
D
Angle/˚
C1 C2 C3 C4 176.1(2)
C17 C18 C19 O3 -179.9(2)
G.M.Sheldrick, Acta Cryst. 2008, A64, 112-122. ...
Final R indexes [all data] R1 = 0.0807, wR2 = 0.1793 Largest diff. peak/hole / e Å -3 0.26/-0.38 Table 2 Bond Lengths for 14 A B C D Angle/˚
A
B
C
D
Angle/˚
O1 C12 C13 C14 178.2(2)
C15 O1 C12 C13 ...
doi:10.6084/m9.figshare.6628103
fatcat:puuavsqpubcq7i6pwoma5c3l6i
Three-dimensional chromatin re-organization during muscle stem cell aging
[article]
2022
bioRxiv
pre-print
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To quantitatively understand how hierarchical chromatin architecture changes during muscle stem cell aging, we generated 3D chromatin conformation maps (Hi-C) and integrated these datasets with multi-omic ...
The authors also thank Anna Shcherbina, and Jie Liu for insights into bioinformatics analysis, and members of the Parker and Aguilar laboratories. ...
ACKNOWLEDGEMENTS The authors thank Arima Genomics for assistance with Hi-C, and the University of Michigan DNA Sequencing Core for assistance with sequencing. ...
doi:10.1101/2022.09.21.508601
fatcat:pmujt6b6pbefxfoxno6aj7inz4
HARNESSING BIG DATA FOR PRECISION MEDICINE: INFRASTRUCTURES AND APPLICATIONS
2016
Biocomputing 2017
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Ram Pressure Candidates in UNIONS
[article]
2021
arXiv
pre-print
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It is confirmed quantitatively with the two-sample Anderson-Darling test (Scholz & Stephens 1987) . ...
EUCLID, the Vera C. Rubin Observatory, the Roman Space Telescope), where the number of galaxies with high-quality imaging will surpass what is practical for by-eye classifications. ...
arXiv:2110.12714v1
fatcat:spvxoz4x2ze5pkpgghptp6rrha
Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations
2019
BMC Immunology
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Subnormal Ig concentrations were defined as those below the corresponding reference limits b Allergic asthma, allergic rhinitis, or allergic dermatitis/eczema c Urticaria, angioedema, or anaphylaxisFig ...
27.3 ± 7.8
26.6 ± 5.7
30.8 ± 12.8
28.1 ± 8.2
Autoimmune condition(s), % (n)
23.1 (3)
42.4 (14)
30.8 (5)
37.3 (22)
Atopy b , % (n)
23.1 (3)
36.4 (12)
15.4 (2)
28.8 (17)
Other allergy c ...
doi:10.1186/s12865-019-0310-3
pmid:31429700
pmcid:PMC6701150
fatcat:736rjwo46jhltkvecfz2dzmuse
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