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Survival Analysis of COVID-19 Patients in Russia Using Machine Learning

Oleg Metsker, Georgy Kopanitsa, Alexey Yakovlev, Karlina Veronika, Nadezhda Zvartau
2020 Studies in Health Technology and Informatics  
In this study we develop analyze mortality for COVID19 patients in Russia. We identify comorbidities and risk factors for different groups of patients including cardiovascular diseases and therapy.  ...  To analyze Features importance for the mortality we have calculated Shapley values for the "mortality" class and ANN hidden layer coefficients for patient lifetime.  ...  The work of Georgy Kopanitsa was financially supported by the Government of the Russian Federation through the ITMO fellowship and professorship program.  ... 
doi:10.3233/shti200644 pmid:33087616 fatcat:gnfpe4qqyfdqjmjj2wrbzpldum

Uncovering clinical risk factors and prediction of severe COVID-19: A machine learning approach based on UK Biobank data [article]

Kenneth C.Y. WONG, Yong Xiang, Hon-Cheong So
2020 medRxiv   pre-print
Shapley dependency and interaction plots were used to evaluate the pattern of relationship between risk factors and outcomes. Results: A total of 2386 severe and 477 fatal cases were identified.  ...  Methods: Based on the UK Biobank(UKBB data), we built machine learning(ML) models to predict the risk of developing severe or fatal infections, and to evaluate major risk factors involved.  ...  Acknowledgements This work was supported partially by the Lo Kwee Seong Biomedical Research Fund from The Chinese University of Hong Kong. We thank Prof.  ... 
doi:10.1101/2020.09.18.20197319 fatcat:oq7tk3a7kvhmdgme3offgbkske

Novel Insights in Spatial Epidemiology Utilizing Explainable AI (XAI) and Remote Sensing

Anastasios Temenos, Ioannis N. Tzortzis, Maria Kaselimi, Ioannis Rallis, Anastasios Doulamis, Nikolaos Doulamis
2022 Remote Sensing  
This novel dataset is evaluated by a tree-based machine learning algorithm that utilizes ensemble learning and is trained to make robust predictions on daily cases and deaths.  ...  In this paper, we propose the fusion of a heterogeneous, spatio-temporal dataset that combine data from eight European cities spanning from 1 January 2020 to 31 December 2021 and describe atmospheric,  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/rs14133074 fatcat:leoysstvubaddmyple3twa2fuq

Global and Local Interpretation of black-box Machine Learning models to determine prognostic factors from early COVID-19 data [article]

Ananya Jana, Carlos D. Minacapelli, Vinod Rustgi, Dimitris Metaxas
2021 arXiv   pre-print
A variety of machine learning models have been applied to related data to predict important factors such as the severity of the disease, infection rate and discover important prognostic factors.  ...  Often the usefulness of the findings from the use of these techniques is reduced due to lack of method interpretability.  ...  They identify a total of 10 features from their 52 feature dataset. Gemmer et.al 18 propose an alternative fuzzy classifier based approach for the task of mortality prediction.  ... 
arXiv:2109.05087v1 fatcat:u4fm5744xzar3har7oyb6vjvmi

Machine Learning Based Prediction of COVID-19 Mortality Suggests Repositioning of Anticancer Drug for Treating Severe Cases [article]

Thomas Linden, Frank Hanses, Daniel Domingo-Fernandez, Lauren Nicole DeLong, Alpha Tom Kodamullil, Jochen Schneider, Maria J.G.T. Vehreschild, Julia Lanznaster, Maria Madeleine Ruethrich, Stefan Borgmann, Martin Hower, Kai Wille (+12 others)
2021 medRxiv   pre-print
In this work, we developed a machine learning model which predicts mortality for COVID-19 patients using data from the multi-center Lean European Open Survey on SARS-CoV-2-infected patients (LEOSS) observational  ...  Altogether, our work demonstrates that interpretation of machine learning based risk models can point towards drug targets and new treatment options, which are strongly needed for COVID-19.  ...  The LEOSS study group contributed at least 5 per mille to the analyses of this study: University Hospital Regensburg (Frank Hanses), Technical University of Munich (Christoph Spinner), University Hospital  ... 
doi:10.1101/2021.11.11.21266048 fatcat:exor633miray7otqopp5bfqria

Predictive models for COVID-19 detection using routine blood tests and machine learning

Yury V. Kistenev, Denis A. Vrazhnov, Ekaterina E. Shnaider, Hala Zuhayri
2022 Heliyon  
This review describes the abilities to develop predictive models for COVID-19 detection using routine blood tests and machine learning.  ...  Data of routine blood tests as a base of SARS-CoV-2 invasion detection allows using the most practical medicine facilities.  ...  A game theory-based Shapley value method can provide a reliable, feature extraction [83, 84] An ensemble learning based on combining several classification algorithms and generating a final prediction  ... 
doi:10.1016/j.heliyon.2022.e11185 fatcat:4qjrlm5gjjbvzis5fzyatahrai

Explainable Artificial Intelligence Methods in Combating Pandemics: A Systematic Review [article]

Felipe Giuste, Wenqi Shi, Yuanda Zhu, Tarun Naren, Monica Isgut, Ying Sha, Li Tong, Mitali Gupte, May D. Wang
2022 arXiv   pre-print
We find that successful use of XAI can improve model performance, instill trust in the end-user, and provide the value needed to affect user decision-making.  ...  We hope this review may serve as a guide to improve the clinical impact of future AI-based solutions.  ...  Benoit Marteau from Bio-MIBLab for his help on reviewing the manuscript. This research was supported by a Wallace H. Coulter Distinguished Faculty Fellowship (M. D.  ... 
arXiv:2112.12705v4 fatcat:g44642qdnfchnmhgzsaqwjacua

eARDS: A multi-center validation of an interpretable machine learning algorithm of early onset Acute Respiratory Distress Syndrome (ARDS) among critically ill adults with COVID-19

Lakshya Singhal, Yash Garg, Philip Yang, Azade Tabaie, A. Ian Wong, Akram Mohammed, Lokesh Chinthala, Dipen Kadaria, Amik Sodhi, Andre L. Holder, Annette Esper, James M. Blum (+5 others)
2021 PLoS ONE  
Clinical data from 35,804 patients who developed ARDS and controls were used to generate predictive models that identify risk for ARDS onset up to 12-hours before satisfying the Berlin criteria.  ...  The machine learning algorithm which provided the best performance exhibited AUROC of 0.89 (95% CI = 0.88–0.90), sensitivity of 0.77 (95% CI = 0.75–0.78), specificity 0.85 (95% CI = 085–0.86).  ...  Acknowledgments Cerner Real-World Data is extracted from the EMR of hospitals (de-identified) in which Cerner has a data use agreement.  ... 
doi:10.1371/journal.pone.0257056 pmid:34559819 fatcat:m76h7iqbenelrphr6fhim6xu5a

COVID-19 mortality risk assessment: An international multi-center study

Dimitris Bertsimas, Galit Lukin, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Bartolomeo Stellato, Holly Wiberg, Sara Gonzalez-Garcia, Carlos Luis Parra-Calderón, Kenneth Robinson, Michelle Schneider, Barry Stein (+8 others)
2020 PLoS ONE  
The CMR model leverages machine learning to generate accurate mortality predictions using commonly available clinical features.  ...  This is the first risk score trained and validated on a cohort of COVID-19 patients from Europe and the United States.  ...  We would like to thank A ´lvaro Fernandez Galiana for helping us to get access to the data sources from Spain and reviewing the manuscript. We would also like to thank Aggelos Stefos, Sarah P.  ... 
doi:10.1371/journal.pone.0243262 pmid:33296405 pmcid:PMC7725386 fatcat:s54swwnprvcsdfi6hrntfaqjqq

COVID Mortality Prediction with Machine Learning Methods: A Systematic Review and Critical Appraisal

Francesca Bottino, Emanuela Tagliente, Luca Pasquini, Alberto Di Napoli, Martina Lucignani, Lorenzo Figà-Talamanca, Antonio Napolitano
2021 Journal of Personalized Medicine  
Particularly, the use of baseline machine learning techniques is rapidly developing in COVID mortality prediction, since a mortality prediction model could rapidly and effectively help clinical decision-making  ...  More than a year has passed since the report of the first case of coronavirus disease 2019 (COVID), and increasing deaths continue to occur.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/jpm11090893 pmid:34575670 pmcid:PMC8467935 fatcat:jtff7snhczbvxnctsyoocmbkvq

Personalized prescription of ACEI/ARBs for hypertensive COVID-19 patients

Dimitris Bertsimas, Alison Borenstein, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Bartolomeo Stellato, Holly Wiberg, Pankaj Sarin, Dirk J. Varelmann, Vicente Estrada, Carlos Macaya, Iván J. Núñez Gil
2021 Health Care Management Science  
We couple electronic medical record (EMR) and registry data of 3,643 patients from Spain, Italy, Germany, Ecuador, and the US with a machine learning framework to personalize the prescription of ACEIs  ...  Our approach leverages clinical and demographic information to identify hospitalized individuals whose probability of mortality or morbidity can decrease by prescribing this class of drugs.  ...  Using machine learning, we are able to identify patients who would benefit the most by receiving this type of medication.  ... 
doi:10.1007/s10729-021-09545-5 pmid:33721153 pmcid:PMC7958102 fatcat:ettnp6raxnhwhfq6fu6323jsla

Factors affecting the COVID-19 risk in the US counties: an innovative approach by combining unsupervised and supervised learning [article]

Samira Ziyadidegan, Moein Razavi, Homa Pesarakli, Amir Hossein Javid, Madhav Erraguntla
2021 arXiv   pre-print
Some states and counties reported high number of positive cases and deaths, while some reported lower COVID-19 related cases and mortality.  ...  In this paper, the factors that could affect the risk of COVID-19 infection and mortality were analyzed in county level.  ...  “Risk Factors of Critical & Mortal COVID-19 Cases: A Systematic Literature Review and Meta- Analysis.” Journal of Infection 81(2): e16–25.  ... 
arXiv:2106.12766v2 fatcat:rzv2e7bfercdvacigtk3dh6r2y

Who's in the Crowd Matters: Cognitive Factors and Beliefs Predict Misinformation Assessment Accuracy

Robert A. Kaufman, Michael Robert Haupt, Steven P. Dow
2022 Proceedings of the ACM on Human-Computer Interaction  
Crowdsourcing can be a means to detect and impede the spread of misinformation online.  ...  However, past studies have not deeply examined the individual characteristics - such as cognitive factors and biases - that predict crowdworker accuracy at identifying misinformation.  ...  ACKNOWLEDGMENTS The authors would like to express gratitude to all of the crowd workers who participated in the task and survey.  ... 
doi:10.1145/3555611 fatcat:ocwc63mk2ngrnl74cvv4w4fqiq

Combining Deep Phenotyping of Serum Proteomics and Clinical Data via Machine Learning for COVID-19 Biomarker Discovery

Antonio Paolo Beltrami, Maria De Martino, Emiliano Dalla, Matilde Clarissa Malfatti, Federica Caponnetto, Marta Codrich, Daniele Stefanizzi, Martina Fabris, Emanuela Sozio, Federica D'Aurizio, Carlo E. M. Pucillo, Leonardo A. Sechi (+7 others)
2022 International Journal of Molecular Sciences  
The main clinical and hematochemical data associated with disease outcome were grouped with serological data to form a dataset for the supervised machine learning techniques.  ...  Importantly, we found three biomarkers associated with central nervous system pathologies and protective factors, which were downregulated in the most severe cases.  ...  Conflicts of Interest: The authors declare no conflict of interest. Int. J. Mol. Sci. 2022, 23, 9161  ... 
doi:10.3390/ijms23169161 pmid:36012423 pmcid:PMC9409308 fatcat:ppwaeosftjdchhwx3wgxar2rsm

Artificial Intelligence: A Review of Progress and Prospects in Medicine and Healthcare

Saurav Mishra
2022 Journal of Electronics Electromedical Engineering and Medical Informatics  
The paper also discusses about the implementation opportunities various AI technologies like Machine Learning, Deep Learning, Reinforcement Learning, Natural Language Processing, Computer Vision provide  ...  A physician's intuition and judgement will always remain better suited since each case, each health condition, and each person is unique in its own way, but AI methods can help enhance the accuracy of  ...  ., [105] use machine learning to improve the prediction of developing a cardiovascular risk.  ... 
doi:10.35882/jeeemi.v4i1.1 fatcat:j2zcn22rl5f77nmy7rmbpr76ma
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