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Application of smart nanostructures in medicine
2010
Nanomedicine
This results in the red-shift of the plasmon absorption due to interparticle plasmon interactions [10] . This method may extend to screening of AChE inhibitors and relevant drug discovery. ...
The development of new techniques for monitoring enzyme secretion in tissue culture is important for fundamental research, bioengineering, toxicology and drug discovery. ...
Application of smart nanostructures in medicine Review www.futuremedicine.com ...
doi:10.2217/nnm.10.81
pmid:20874025
fatcat:zg45kdrlaven3nmdcevrxzshgu
Medical Nanorobot Architecture Based on Nanobioelectronics
2007
Recent Patents on Nanotechnology
This provides useful directions for further research and development of medical nanorobotics and suggests a time frame in which nanorobots may be expected to be available for common utilization in therapeutic ...
This work describes an innovative medical nanorobot architecture based on important discoveries in nanotechnology, integrated circuit patents, and some publications, directly or indirectly related to one ...
Wood, for their helpful comments. This project was partially supported by the Australian Research Council (ARC). ...
doi:10.2174/187221007779814745
pmid:19076015
fatcat:ksodjohfojabpg4kssm7shtqzm
Advances of medical nanorobots for future cancer treatments
2023
Journal of Hematology & Oncology
With the progress of nanotechnology, nanobots enable the assembly and deployment of functional molecular/nanosized machines and are increasingly being utilized in cancer diagnosis and therapeutic treatment ...
In this paper, we review and analyze the recent advancements of nanobots in cancer treatments, with a particular emphasis on their key fundamental features and their applications in drug delivery, tumor ...
The logic-gated recognition integrated into inducer-functionalized molecular machines enables rapid cancer dissection, in situ trapping and separation, and the safe delivery of precision medicine. ...
doi:10.1186/s13045-023-01463-z
pmid:37452423
pmcid:PMC10347767
fatcat:a5fofgihfve2voi4xkgiukapka
Nanomanipulation in Biomedical Applications
2021
Current Robotics Reports
As an enabling technology, nanorobotic manipulation provides the capability to the control of position and orientation of an object. ...
Purpose of Review Progress in nanorobotics over the past decades has dramatically extended our ability to explore the world down to individual molecules/atoms. ...
Min Ju Shon et al. developed an MT-based method for precise force-extension measurements in the 100-nm regime that enables in situ correction of the error in DNA extension measurement [65]. ...
doi:10.1007/s43154-021-00047-4
fatcat:lgapxej5w5fbxdaxku7dg265ri
Nanomedicine: Application of Nanobiotechnology in Medical Practice
2008
Medical Principles and Practice
This article starts with the basics of nanobiotechnology, followed by its applications in molecular diagnostics, nanodiagnostics, and improvements in the discovery, design and delivery of drugs, including ...
Numerous applications in the pharmaceutical industry such as drug discovery and drug delivery can be covered under the term 'nanobiopharmaceuticals'. ...
Apart from refinements in molecular diagnostics, an important basis of personalized medicine, nanobiotechnology also helps in the discovery of biomarkers that are crucial for the development of personalized ...
doi:10.1159/000112961
pmid:18287791
fatcat:vcyzhniikfcexod273g7dbzo5i
Recent Process in Microrobots: From Propulsion to Swarming for Biomedical Applications
2022
Micromachines
In particular, the locomotion of these micro/nanorobots, as well as the requirement of biocompatibility, transportation efficiency, and controllable motion for applications in the complex human body environment ...
Inspired by the motion pattern and collective behaviors of the tiny biological motors in nature, various kinds of sophisticated and programmable microrobots are fabricated with the ability for cargo delivery ...
For example, some bacteria have a molecular motor in their bodies that controls the helical rotation of the flagellum, which actuate the movement of the bacteria. ...
doi:10.3390/mi13091473
pmid:36144096
pmcid:PMC9503943
fatcat:rjpd2lhwsfdvnkjqcx2hs3isyq
Nanodiagnostics: A Revolution in Biomedical Nanotechnology
2016
MOJ Proteomics & Bioinformatics
The application of nanobiotechnology in molecular diagnostics is termed nanodiagnostics, and it offers new and exciting options for personalized cancer therapy. ...
The incorporation of nanobiotechnology with molecular diagnostics deploys 'nanoscale probes' for detailed analysis of cell components that exist in nanoscale dimensions. ...
Nanoparticles in the discovery of biomarkers Biomedical nanotechnology can replace the current molecular diagnostic technologies for the detection of biomarkers. ...
doi:10.15406/mojpb.2016.03.00080
fatcat:lv2qdlmd7zfpnjxhhexfv6bosy
Overview of DNA Self-Assembling: Progresses in Biomedical Applications
2018
Pharmaceutics
Molecular self-assembling is ubiquitous in nature providing structural and functional machinery for the cells. ...
Herein, we summarize the recent advances made in the designing of DNA nanostructures with special emphasis on their application in biomedical research as imaging and diagnostic platforms, drug, gene, and ...
The dynamic nature of 'sense-and-treat' device plays a major role in the construction of a sensitive and robust molecular sensing while inducing specific cell death. ...
doi:10.3390/pharmaceutics10040268
pmid:30544945
pmcid:PMC6320858
fatcat:mzwybyhhxfd6lniwvz5wuj5vaa
Optimization of Protein-Protein Interaction Measurements for Drug Discovery Using AFM Force Spectroscopy
2019
IEEE transactions on nanotechnology
Increasingly targeted in drug discovery, protein-protein interactions challenge current high throughput screening technologies in the pharmaceutical industry. ...
Developing an effective and efficient method for screening small molecules or compounds is critical to accelerate the discovery of ligands for enzymes, receptors and other pharmaceutical targets. ...
Li for his help in experimental techniques. The authors would like to thank Dr. J. Yu for her help on arranging the experiments. ...
doi:10.1109/tnano.2019.2915507
pmid:32051682
pmcid:PMC7015265
fatcat:ddtr2k5xjzajtb3ujma76bolge
Medicine Soaring with Nanofever
2018
Journal of Nanosciences Current Research
Sumrrita Saroch for their selfless support throughout. ...
radio control which can enable targeted drug release in human bloodstream [24] . ...
Nanorobots
Design of nanorobots It is derived from biological models typically, 650 nm in length and 160 nm in diameter. ...
doi:10.4172/2572-0813.1000120
fatcat:vewvcywi6nh2vnnnp5tshbl6bu
Applications of Nanobiotechnology in Clinical Diagnostics
2007
Clinical Chemistry
Safety studies are needed for in vivo use. ...
Results: Nanotechnologies enable diagnosis at the single-cell and molecule levels, and some can be incorporated in current molecular diagnostic methods, such as biochips. ...
Sensing in picoliter to attoliter volumes might create new problems in the development of microreactors for sensing and novel phenomena in very small channels. ...
doi:10.1373/clinchem.2007.090795
pmid:17890442
fatcat:4iop37xqong4nbyximev6y7xli
Synthetic biology devices for in vitro and in vivo diagnostics
2015
Proceedings of the National Academy of Sciences of the United States of America
Synthetic biology devices, such as engineered gene circuits, bring new capabilities to molecular diagnostics, expanding the molecular detection palette, creating dynamic sensors, and untethering reactions ...
There is a growing need to enhance our capabilities in medical and environmental diagnostics. ...
Although there is great potential for such tools, the in vivo susceptibility of DNA-based nanorobots to degradation must be addressed before use in humans; but, encouragingly, nanorobots have been successfully ...
doi:10.1073/pnas.1508521112
pmid:26598662
pmcid:PMC4664311
fatcat:f236fhocnzd4lffmtvkoztmwky
Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications
2019
Advanced Healthcare Materials
of a target analyte, resulting in numerous smart nanoprobes for diverse applications including intracellular imaging, drug delivery, in vivo imaging, and tumor therapy. ...
Benefiting from the recent progress of molecular engineering strategies, the physicochemical properties of nanomaterials are endowed by the target recognition and catalytic activity of FNAs in the presence ...
[99] who developed a multiple aptamer/nGO based sensing platform for simultaneous monitoring of ATP and GTP in situ. Recently, Yi et al. ...
doi:10.1002/adhm.201801158
pmid:30725526
pmcid:PMC6426685
fatcat:fpz4o7c4wzcr3kxkew6ejvo3ba
DNA-Based Fluorescent Nanoprobe for Cancer Cell Membrane Imaging
2024
Molecules
In addition, DNA nanomaterials can be combined with the cell membrane in a specific manner to enable the real-time imaging of signal molecules on the cell membrane, allowing for the real-time monitoring ...
First, we present the conditions for imaging DNA nanomaterials in the cell membrane microenvironment, such as the ATP, pH, etc. ...
[69] designed an i-motif with a hairpin as an acid response element and paired it with a tumor-targeting nucleic acid aptamer for the bispecific imaging and in situ drug release of tumor cells, dubbing ...
doi:10.3390/molecules29010267
pmid:38202850
pmcid:PMC10780466
fatcat:3bqzkandsbhotdkd4fjtwtfxri
Nanoscale Architectures for Smart Bio-Interfaces: Advances and Challenges
[chapter]
2011
Nanofabrication
For example, the in situ cell pH sensor was mapped in situ with SERS and gold nanoparticles functionalized with 4-mercapto-benzoic acid. ...
A selective, in situ detection with OTFTs requires a versatile method for the immobilization of various selective molecular probes within proximity to the active transport channel. ...
doi:10.5772/28893
fatcat:lkd3h4ilvvhyhfcpq7dxcdhqli
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