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Biomarkers in Ocular Chronic Graft Versus Host Disease: Tear Cytokine- and Chemokine-Based Predictive Model
2016
Investigative Ophthalmology and Visual Science
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normal T cell expressed and secreted [RANTES]) were measured by multiplex-bead assay and correlated with clinical parameters. ...
Classification capacity was evaluated in a cohort of individuals with dry eye (DE) of other etiologies different from GVHD. RESULTS. ...
lymphoblastic leukemia
24
63
None
None
4
Acute myeloid leukemia
12
60
None
Autologous serum
0.1% preserved
fluorometholone
5
Acute myeloid leukemia
3
126
Cyclosporine A
None
6
Hodgkin ...
doi:10.1167/iovs.15-18615
pmid:26927568
fatcat:vrlzntiburgefnw7gak2vog2qe
Using Self-Organizing Maps to Visualize, Filter and Cluster Multidimensional Bio-Omics Data
[chapter]
2012
Applications of Self-Organizing Maps
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AML: acute myeloid leukemia; ALL: acute lymphoblastic leukemia; ALL_B: B-cell ALL; ALL_T: T-cell ALL. ...
These samples include 11 acute myeloid leukemia (AML) and 27 acute lymphoblastic leukemia (ALL) that can be further sub-typed into 19 B-cell ALL (ALL_B) and 8 T-cell ALL (ALL_T). ...
doi:10.5772/51702
fatcat:ic6d6rurcbf73ldmj56iioo6ca
A Pyramid Model of Convolutional Neural Network to Classify Acute Lymphoblastic Leukemia Images
2022
International Journal of Intelligent Engineering and Systems
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We have evaluated our proposed architecture using acute lymphoblastic leukemia image database (ALL-IDB2). ...
Many researchers have classified acute lymphoblastic leukemia using several methods. One of the methods is a convolutional neural network. ...
Based on the above explanations, we proposed a new convolutional neural network architecture to classify the acute lymphoblastic Leukemia images. ...
doi:10.22266/ijies2022.1231.51
fatcat:yfjzheopcvf3hnxkz4d66gqj7e
Simultaneous Evaluation of Terminal Deoxynucleotidyl Transferase and Myeloperoxidase in Acute Leukemias Using an Immunocytochemical Method
1987
American Journal of Clinical Pathology
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The classification of acute leukemia is important for the selection of optimal therapy. ...
This finding supports the hypothesis that TdT is an expression of cell primitivity rather than a marker for lymphoblastic cells. ...
2) leukemias and 12 of 16 acute lymphoblastic (TdT+ CALLA+) leukemias but failed to react with more differentiated acute leukemias. ...
doi:10.1093/ajcp/87.6.732
pmid:3035914
fatcat:kq6ddxzpo5dyrfpwutoasqghge
Analysis of Argyrophilic Nucleolar Organizer Regions (AgNORs) in Acute Leukemia in Adults
2022
Diagnostics
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In leukemic cells, the mean AgNORs number, mean AgNORs area, and mean AgNOR-area-to-nucleus-area ratio were calculated in patients with acute myeloid leukemia (AML), patients with acute lymphoblastic leukemia ...
Bone marrow aspirates from 70 patients with acute leukemia underwent morphological, immunophenotypic, and genetic assessment and were stained with silver nitrate. ...
); (d) acute lymphoblastic leukemia (Philadelphia+). ...
doi:10.3390/diagnostics12040832
pmid:35453880
pmcid:PMC9027282
fatcat:6en6j5n3zvec7ga7narifwzl3e
Comprehensive profiling of disease-relevant copy number aberrations for advanced clinical diagnostics of pediatric acute lymphoblastic leukemia
2019
Modern Pathology
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In this study, disease-relevant copy number aberrations were profiled in bone marrow samples of 91 children with B- or T-cell precursor acute lymphoblastic leukemia using digital multiplex ligation-dependent ...
A newly introduced risk classifier combining cytogenetic data with digitalMLPATM-based copy number aberration profiles allowed for the determination of four genetic subgroups of B-cell precursor acute ...
This suggests that the digitalMLPA TM -based classification may potentially provide further improvement in the risk assessment of patients with B-cell precursor acute lymphoblastic leukemia, which therefore ...
doi:10.1038/s41379-019-0423-5
pmid:31857684
fatcat:6465yvfxcvga7jhcyptu6pu5bi
The Profile of BCR-ABL1 Fusion Gene in Childhood Leukemia at "Dharmais" Cancer Hospital
2020
Indonesian Journal of Cancer
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A total of 74.7% (59/79) patients were diagnosed with Chronic Myelogenous Leukemia (CML), 21.5% (17/79) with Acute Lymphoblastic Leukemia (ALL), and 3.8% (3/79) with Acute Myelogenous Leukemia (AML). ...
leukemia who performed the BCR-ABL1 examination in "Dharmais" Cancer Hospital during 2008–2018. ...
Table 1 . 1 Characteristics of respondents based on sex, leukemia type, and ages ALL: acute lymphoblastic leukemia, AML: acute myeloid leukemia, CML: chronic myeloid leukemia Characteristics
n (%)
Gender ...
doi:10.33371/ijoc.v14i3.729
fatcat:g55a2wn4xnfkpdbs4obb3qvi6a
Explainable AI in Diagnosing and Anticipating Leukemia Using Transfer Learning Method
2022
Computational Intelligence and Neuroscience
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The proposed strategy recognizes acute lymphoblastic leukemia as an automated procedure that applies different transfer learning models to classify ALL. ...
Acute lymphocytic leukemia (ALL) usually occurs when the bone marrow creates many immature WBCs that destroy healthy cells. ...
Leukemia is classified primarily based on whether it is increasing rapidly (acute) or slowly (chronic). Each of these types can be fatal if not detected or if therapy is delayed. ...
doi:10.1155/2022/5140148
pmid:35528341
pmcid:PMC9068323
fatcat:xcpcu5r7zbgqjhqcxlqwzbv7wq
Acute Lymphoblastic Leukemia Presenting as Systemic Juvenile Idiopathic Arthritis: Experience from Bangladesh
2024
Open Journal of Rheumatology and Autoimmune Diseases
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Acute lymphoblastic leukemia (ALL), the most common paediatric malignancy, is a heterogeneous hematologic disease. ...
Conclusion: The presentation of leukemia with arthralgia or arthritis makes the diagnosis difficult for the physicians. ...
Introduction Acute lymphoblastic leukemia (ALL) is a heterogeneous hematologic disease characterized by the proliferation of immature lymphoid cells in the bone marrow, peripheral blood, and other organs ...
doi:10.4236/ojra.2024.141001
fatcat:zaxsoqq6vrg4fg3iismxq6xag4
Mechanisms of Immune Evasion in Acute Lymphoblastic Leukemia
2021
Cancers
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Acute lymphoblastic leukemia (ALL) results from a clonal expansion of abnormal lymphoid progenitors of B cell (BCP-ALL) or T cell (T-ALL) origin that invade bone marrow, peripheral blood, and extramedullary ...
In addition, we describe how developing leukemia shapes the bone marrow microenvironment and alters the function of immune cells. ...
Table 2 . 2 [28,29]ar subtypes in T cell acute lymphoblastic leukemia, based on[28,29]. ...
doi:10.3390/cancers13071536
pmid:33810515
pmcid:PMC8037152
fatcat:ytck7tq7izdotdwh2hz4xtx33i
Sudden bilateral visual loss in acute myeloid leukaemia
2000
British Journal of Ophthalmology
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Acute leukemia presenting as a retinal
pigment epithelium detachment. Arch Ophthal-
mol 1988;106:21-2.
4 Stewart MW, Gitter KA, Cohen G. ...
old woman with a diagnosis of acute myeloid leukaemia FAB (French, American, British) classification M1, was started on BF-12 chemotherapy consisting of a combination of cytarabine, etoposide, and idarubicin ...
Basal cell carcinomas have been reported to arise from a previous cutaneous leishmaniasis lesion. 9 10 To our knowledge, this is the first case of development of a squamous cell carcinoma from a previous ...
doi:10.1136/bjo.84.11.1318
pmid:11203167
pmcid:PMC1723303
fatcat:dyf5ssa24jhx3lbvjti77rwu5e
ANKHD1, ankyrin repeat and KH domain containing 1, is overexpressed in acute leukemias and is associated with SHP2 in K562 cells
2006
Biochimica et Biophysica Acta - Molecular Basis of Disease
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Furthermore, a higher expression of ANKHD1 mRNA was detected in primary acute leukemia samples than in normal hematopoietic cells (P = 0.002). ...
In the present study, increased levels of ANKHD1 mRNA and protein expression in leukemia cell lines are reported, as compared with normal hematopoietic cells. ...
State University of Campinas were studied, including 7 ALL, 1 biphenotypic acute leukemia and 30 AML (1 M0, 5 M1, 6 M2, 3 M3, 10 M4, 3 M5, 1 M6, 1 M7) based on the French-American-British (FAB) classification ...
doi:10.1016/j.bbadis.2006.07.010
pmid:16956752
fatcat:4tjonjclxfcdbdfispo7k7tosa
Targeting the lncRNA DUXAP8/miR-29a/PIK3CA Network Restores Doxorubicin Chemosensitivity via PI3K-AKT-mTOR Signaling and Synergizes With Inotuzumab Ozogamicin in Chemotherapy-Resistant B-Cell Acute Lymphoblastic Leukemia
2022
Frontiers in Oncology
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PurposeThis study aimed to determine the expression profiles of long non-coding RNA (lncRNA), microRNA (miRNA), and mRNA in chemotherapy-resistant B-cell acute lymphoblastic leukemia (B-ALL).MethodsLncRNA ...
in chemoresistant patient samples, and its effect on cellular phenotypes, PI3K-AKT-mTOR signaling, and chemosensitivity of doxorubicin (Dox)-resistant Nalm-6 (N6/ADR), and Dox-resistant 697 (697/ADR) cells ...
acute lymphoblastic leukemia (B-ALL). ...
doi:10.3389/fonc.2022.773601
pmid:35311115
pmcid:PMC8924619
fatcat:soiluccv2ffflfl6rizq7hwlya
Single-cell transcriptomics predicts relapse in MLL-rearranged acute lymphoblastic leukemia in infants
[article]
2020
medRxiv
pre-print
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Infants with MLL-rearranged acute lymphoblastic leukemia (ALL) undergo intense therapy to counter a highly aggressive leukemia with survival rates of only 30-40%. ...
Strikingly, the single-cell based classification is even consistent with the order of relapse timing. ...
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol. 2003;21(17):3262-3268. 40. ...
doi:10.1101/2020.04.14.20056580
fatcat:2tkgtfrhifhdxaqqn3mu6bixaa
A semantics-oriented computational approach to investigate microRNA regulation on glucocorticoid resistance in pediatric acute lymphoblastic leukemia
2018
BMC Medical Informatics and Decision Making
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resistance in pediatric acute lymphoblastic leukemia. ...
Acute lymphoblastic leukemia is the most prevalent neoplasia among children. ...
Background Acute lymphoblastic leukemia (ALL) is the most common childhood malignant tumor and accounts for about 80-85% of acute leukemia in children. ...
doi:10.1186/s12911-018-0637-3
pmid:30066657
pmcid:PMC6069764
fatcat:ote5suu4jzemfaiuhe5qz7mfaa
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