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Variational Inference over Combinatorial Spaces

Alexandre Bouchard-Côté, Michael I. Jordan
2010 Neural Information Processing Systems  
We propose a new framework that extends variational inference to a wide range of combinatorial spaces.  ...  Because of this, in applications to combinatorial spaces simple exact models are often preferred to more complex models that require approximate inference [4] .  ...  There has been work on applying variational algorithms to the problem of maximization over combinatorial spaces [11, 12, 13, 14] , but maximization over combinatorial spaces is rather different than summation  ... 
dblp:conf/nips/Bouchard-CoteJ10 fatcat:hl7jp7pt5vdv3h22gjjmlbahke

Algorithmic approaches to clonal reconstruction in heterogeneous cell populations

Wazim Mohammed Ismail, Etienne Nzabarushimana, Haixu Tang
2019 Quantitative Biology  
We categorize these methods based on the type of input data that they use (space-resolved or time-resolved), and also based on their computational formulation as either combinatorial or probabilistic.  ...  In this paper, we review the theoretical framework and assumptions over which the clonal reconstruction problem is formulated.  ...  It uses Bayesian inference based on Markov Chain Monte Carlo (MCMC) sampling algorithm to infer a distribution over phylogenies, where the Dirichlet distribution over all potential phylogenies is used  ... 
doi:10.1007/s40484-019-0188-3 pmid:32431959 pmcid:PMC7236794 fatcat:rcigo5p6evbylh2s2jh4xshpcu

Variational Combinatorial Sequential Monte Carlo Methods for Bayesian Phylogenetic Inference [article]

Antonio Khalil Moretti, Liyi Zhang, Christian A. Naesseth, Hadiah Venner, David Blei, Itsik Pe'er
2021 arXiv   pre-print
We introduce Variational Combinatorial Sequential Monte Carlo (VCSMC), a powerful framework that establishes variational sequential search to learn distributions over intricate combinatorial structures  ...  Bayesian phylogenetic inference is often conducted via local or sequential search over topologies and branch lengths using algorithms such as random-walk Markov chain Monte Carlo (MCMC) or Combinatorial  ...  VARIATIONAL COMBINATORIAL SEQUENTIAL MONTE CARLO Variational Objective.  ... 
arXiv:2106.00075v2 fatcat:jnz5etloqzawxfcaqm5cwswvfq

Large-scale learning of combinatorial transcriptional dynamics from gene expression

H. M. Shahzad Asif, Guido Sanguinetti
2011 Computer applications in the biosciences : CABIOS  
Results: We present a novel method to infer combinatorial regulation of gene expression by multiple transcription factors in largescale transcriptional regulatory networks.  ...  Direct experimental measurement of TFs' activities is, however, challenging, resulting in a need to develop statistical tools to infer TF activities from mRNA expression levels of target genes.  ...  We then ran the variational EM algorithm to infer the posterior probabilities over TF states and gene-specific parameters, and compared with the true parameter values/ TF states.  ... 
doi:10.1093/bioinformatics/btr113 pmid:21367870 fatcat:j7mvcqjfsndk3hb3xo353l6xz4

Combinatorial Markov Random Fields [chapter]

Ron Bekkerman, Mehran Sahami, Erik Learned-Miller
2006 Lecture Notes in Computer Science  
A combinatorial random variable is a discrete random variable defined over a combinatorial set (e.g., a power set of a given set).  ...  Since it can be problematic to apply existing inference techniques for graphical models to Comrafs, we design two simple and efficient inference algorithms specific for Comrafs, which are based on combinatorial  ...  Finally, defineX c to be a combinatorial r.v. with the event space X c .  ... 
doi:10.1007/11871842_8 fatcat:62utnn6p45h37bimgl3bcjsnni

Provable Variational Inference for Constrained Log-Submodular Models

Josip Djolonga, Stefanie Jegelka, Andreas Krause
2018 Neural Information Processing Systems  
To perform inference in these models we design novel variational inference algorithms, which carefully leverage the combinatorial and probabilistic properties of these objects.  ...  These capture log-submodular dependencies of arbitrary order between the variables, but also satisfy hard combinatorial constraints.  ...  Bouchard-Côté and Jordan [5] introduce a class of variational techniques over combinatorial spaces, but they make a different set of assumptions -they assume a product space and models that are tractable  ... 
dblp:conf/nips/DjolongaJ018 fatcat:ag4xpvgvzrh4jnx5o4xckcoyc4

Probabilistic Subgraph Matching Based on Convex Relaxation [chapter]

Christian Schellewald, Christoph Schnörr
2005 Lecture Notes in Computer Science  
close-to-optimal combinatorial matchings within the original solution space.  ...  We show that the global minimum of the relaxed convex problem can be interpreted as probability distribution over the original space of matching matrices, providing a basis for efficiently sampling all  ...  the original combinatorial solution space.  ... 
doi:10.1007/11585978_12 fatcat:un4ojokbnnb47limhmm5h727p4

Variational Causal Networks: Approximate Bayesian Inference over Causal Structures [article]

Yashas Annadani, Jonas Rothfuss, Alexandre Lacoste, Nino Scherrer, Anirudh Goyal, Yoshua Bengio, Stefan Bauer
2021 arXiv   pre-print
To this end, we introduce a parametric variational family modelled by an autoregressive distribution over the space of discrete DAGs.  ...  Aiming to overcome this issue, we propose a form of variational inference over the graphs of Structural Causal Models (SCMs).  ...  the combinatorial nature of the space of DAGs [15] .  ... 
arXiv:2106.07635v1 fatcat:rjiotac6nvhlla6tnv2caoncia

Sequence to Better Sequence: Continuous Revision of Combinatorial Structures

Jonas Mueller, David K. Gifford, Tommi S. Jaakkola
2017 International Conference on Machine Learning  
To avoid combinatorial-search over sequence elements, we specify a generative model with continuous latent factors, which is learned via joint approximate inference using a recurrent variational autoencoder  ...  Under this model, gradient methods can be used to efficiently optimize the continuous latent factors with respect to inferred outcomes.  ...  By exploiting such simplified geometry, a basic shift in the latent vector space may be able to produce higher-quality revisions than attempts to directly manipulate the combinatorial space of sequence  ... 
dblp:conf/icml/MuellerGJ17 fatcat:acldrozqvbd6fnqogrhhefwctu

Space in weak propositional proof systems

Ilario Bonacina
2016 Bulletin of the European Association for Theoretical Computer Science  
This year's award went to Ilario Bonacina for his thesis Space in weak propositional proof systems, which was supervised by Nicola Galesi at the University of Rome "La Sapienza".  ...  Ilario's thesis contributes to a classic and deep topic in theoretical computer science, and settles natural questions on the space complexity of proofs using Resolution and the Polynomial Calculus that  ...  This technical construction relies on some combinatorial games over bipartite graphs, the Cover Games, and to some variations of Hall's theorem to objects similar to matchings, V-matchings and VW-matchings  ... 
dblp:journals/eatcs/Bonacina16 fatcat:7oxgzcxtdnf4bfpncyd27bhshe

Novelty and imitation within the brain: a Darwinian neurodynamic approach to combinatorial problems

Dániel Czégel, Hamza Giaffar, Márton Csillag, Bálint Futó, Eörs Szathmáry
2021 Scientific Reports  
AbstractEfficient search in vast combinatorial spaces, such as those of possible action sequences, linguistic structures, or causal explanations, is an essential component of intelligence.  ...  We demonstrate that the emerging Darwinian population of readout activity patterns is capable of maintaining and continually improving upon existing solutions over rugged combinatorial reward landscapes  ...  Mutations generate variation through which the space of possible solutions is explored.  ... 
doi:10.1038/s41598-021-91489-5 pmid:34131159 pmcid:PMC8206098 fatcat:hwugkfhghvgelbljb5uecmjuea

CPlaNet: Enhancing Image Geolocalization by Combinatorial Partitioning of Maps [article]

Paul Hongsuck Seo, Tobias Weyand, Jack Sim, Bohyung Han
2018 arXiv   pre-print
To tackle this issue, we propose a simple but effective algorithm, combinatorial partitioning, which generates a large number of fine-grained output classes by intersecting multiple coarse-grained partitionings  ...  In terms of space complexity, classification based methods definitely have great advantages over retrieval based ones, which need to maintain the entire image database.  ...  Moreover, our model, like other classification-based approaches, requires much less space than the retrieval-based models for inference.  ... 
arXiv:1808.02130v1 fatcat:pd4x6iaknndoxkkzui3ltqs43m

Pantypes: Diverse Representatives for Self-Explainable Models [article]

Rune Kjærsgaard, Ahcène Boubekki, Line Clemmensen
2024 arXiv   pre-print
These classifiers are designed to incorporate high transparency in their decisions by basing inference on similarity with learned prototypical objects.  ...  We show that pantypes can empower prototypical self-explainable models by occupying divergent regions of the latent space and thus fostering high diversity, interpretability and fairness.  ...  The values are the mean and standard deviation over three runs.  ... 
arXiv:2403.09383v1 fatcat:d5bjfmtdyneylmpmtrdey4hgsa

Directional Statistics on Permutations [article]

Sergey M. Plis and Terran Lane and Vince D. Calhoun
2010 arXiv   pre-print
As a demonstration of the benefits of the framework we derive an inference procedure for a state-space model over permutations. We demonstrate the approach with applications.  ...  It makes the direct definition of a multinomial distribution over permutation space impractical for all but a very small n. In this work we propose an embedding of all n!  ...  -Practical results: we develop efficient inference over permutations in a state-space model. * We employ analytical product and marginalization operations. * We show efficient transformation of partially  ... 
arXiv:1007.2450v1 fatcat:6llt3gmeavcwxjap4r2hnky2vi

Compact Rule Extraction for Hierarchical Phrase-based Translation

Baskaran Sankaran, Gholamreza Haffari, Anoop Sarkar
2020 Conference of the Association for Machine Translation in the Americas  
The first is a combinatorial optimization approach and the second is a Bayesian model over Hiero grammars using Variational Bayes for inference.  ...  We use Variational Bayes (VB) for inference.  ...  Variational Inference for our Model We now describe the Variational inference procedure for our model explained earlier in Section 4.1.  ... 
dblp:conf/amta/SankaranHS20 fatcat:q7l4dzmszjcwlctfjfoyy2vere
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