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This changes to that : Combining causal and non-causal explanations to generate disease progression in capsule endoscopy
[article]
2022
arXiv
pre-print
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In this work, we propose a unified explanation approach that given an instance combines both model-dependent and agnostic explanations to produce an explanation set. ...
We use Wireless Capsule Endoscopy (WCE) domain to illustrate the effectiveness of our explanations. ...
To the best of our knowledge, this is one of the first works to propose a single framework for generating both causal as well as non-causal explanation for deep learning based models. ...
arXiv:2212.02506v1
fatcat:gzj5ed275begxkofj2viqojefa
Endoscopy in patients with diarrhea during treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitors: Is the cause in the mucosa?
2016
Acta Oncologica
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Although these abnormalities provide insufficient explanation for the occurrence of diarrhea, we suggest to perform routine upper GI endoscopy in VEGFR TKItreated patients with GI complaints. ...
Gastroduodenoscopy revealed gastro-esophageal reflux disease, bulbitis and/or duodenitis with ulcers in eight patients. ...
Due to the non-prospective nature of our study, a causal relationship between the reflux disease and the use of VEGFR TKI could not be evaluated. ...
doi:10.3109/0284186x.2015.1119883
pmid:26959411
fatcat:4l7n2ogprbd7rjbqtkdibmiqku
Capturing the Biologic Onset of Inflammatory Bowel Diseases: Impact on Translational and Clinical Science
2019
Cells
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Late diagnosis in IBD is due to the lack of accurate, non-invasive indicators that would allow disease identification during the pre-clinical stage—as it is often done in many other medical conditions. ...
While much progress has been made in the last two decades in the treatment and the management of inflammatory bowel diseases (IBD)—both ulcerative colitis (UC) and Crohn's Disease (CD)—as of today these ...
Acknowledgments: Writing of this review did not require financial support.
Conflicts of Interest ...
doi:10.3390/cells8060548
pmid:31174359
pmcid:PMC6627618
fatcat:3iwigb2ky5gv3l5io7fsvnmb7y
Explainable artificial intelligence (XAI) in deep learning-based medical image analysis
[article]
2021
arXiv
pre-print
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Papers on XAI techniques in medical image analysis are then surveyed and categorized according to the framework and according to anatomical location. ...
This survey presents an overview of eXplainable Artificial Intelligence (XAI) used in deep learning-based medical image analysis. ...
They showed that adding this loss aids in generating better textual explanation. ...
arXiv:2107.10912v1
fatcat:kxbjnnt4hjbmvkgnthkzaq2vwe
The Current Status of Molecular Biomarkers for Inflammatory Bowel Disease
2022
Biomedicines
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Although the specificity and accuracy of laboratory testing alone need to be improved, it is increasingly used to monitor disease activity or to diagnose suspected IBD cases in combination with endoscopy ...
This review introduces currently available non-invasive biomarkers of clinical importance in laboratory testing for IBD, and discusses the trends and challenges in the IBD biomarker studies. ...
Karger AG, Basel publishers for reusing the Figure for our review's Figure 2 from the journal Digestive Diseases (2021; 39: 190-203, https://doi.org/10.1159/000511641), and thank the MDPI for reusing ...
doi:10.3390/biomedicines10071492
pmid:35884797
pmcid:PMC9312796
fatcat:flt45psxtfgb5mhrd24hsqzvhy
Diagnosing small bowel Crohn's disease with wireless capsule endoscopy * Authors' reply
2003
Gut
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Log onto our website (www.gutjnl.com), find the paper that interests you, and send your response via email by clicking on the "eLetters" option in the box at the top right hand corner. ...
If you have a burning desire to respond to a paper published in Gut, why not make use of our "rapid response" option? ...
This study was observational and not aimed at establishing causal links, a goal that requires a combination of prospective clinical studies and careful in vitro experiments. ...
doi:10.1136/gut.52.10.1531-b
pmid:12970152
pmcid:PMC1773840
fatcat:pzvmcocubjdhjmrjmc6gjrscue
Big data in IBD: big progress for clinical practice
2020
Gut
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In this narrative review, we discuss how big data integration and machine learning have been applied to translational IBD research. ...
Approaches such as machine learning may enable patient stratification, prediction of disease progression and therapy responses for fine-tuning treatment options with positive impacts on cost, health and ...
assessment of wireless capsule endoscopy data. ...
doi:10.1136/gutjnl-2019-320065
pmid:32111636
pmcid:PMC7398484
fatcat:64i6abikczhvbjwabgvp6cxyke
Malignancies in Inflammatory Bowel Disease
2020
Digestion
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Moreover, novel biological drugs have been introduced in clinical practice and have dramatically changed long-term IBD management. ...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, primarily of, but not restricted to, the gut. ...
Funding Sources This work was supported by a grant from the Swiss National Science Foundation to TG (Grant No. P2ZHP3_168561). ...
doi:10.1159/000509544
pmid:32799195
fatcat:4ommac63y5hbzp4n4eza4qca3q
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) – a Helicobacter-opposite point
2021
Baillière's Best Practice & Research : Clinical Gastroenterology
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Unlike sporadic gastric cancer, Helicobacter pylori is usually absent in patients with GAPPS. This opposite-point finding has so far not been fully clarified. ...
Prophylactic total gastrectomy is indicated in all cases of GAPPS with fundic gland polyposis and the presence of any dysplasia. ...
Acknowledgements The authors are grateful to Ian McColl, MD, PhD for assistance with the manuscript. ...
doi:10.1016/j.bpg.2021.101728
pmid:33975682
fatcat:cv6wkbvab5g5dghl32jsgnup3i
Nutritional prevention of colorectal cancer
2020
Proceedings of the Nutrition Society
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risk of this common malignancy. ...
There is intense interest in nutritional therapy of patients after diagnosis of CRC, in order to impact on recurrence and overall survival (now often termed cancer interception). ...
H. wishes to thank the Organising Committee for the invitation to speak at the Nutrition Society Winter Conference 2019: Diet and Digestive Disease. ...
doi:10.1017/s0029665120000051
pmid:32019626
fatcat:62rfkmovfjfrfcwted6ysosyvy
Current Trends in the Management of Gastroesophageal Reflux Disease: A Review
2012
ISRN Gastroenterology
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In the last 30 to 40 years, research findings have given rise to a more robust understanding of its pathophysiology, clinical presentation, and management. ...
A substantial proportion of GERD patients continue to have symptoms despite optimal PPI therapy, and this has necessitated research into the development of new drugs. ...
Possible explanations for this include aging population, the obesity epidemic (and associated changes in diet or physical activity), and changes in sleep pattern [11] . ...
doi:10.5402/2012/391631
pmid:22844607
pmcid:PMC3401535
fatcat:ztpcdh52tvbtzc4m3i3ta5cyxm
New British Society of Gastroenterology (BSG) guidelines for the diagnosis and management of Barrett's oesophagus
2006
Gut
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necessary to understand the mechanisms of p31-49 signalling and its effects on intestinal mucosa, how this is linked to IL-15 production, and why these changes should only occur in coeliac disease. ...
). 1 In this article, the main changes in recommendations are highlighted and their value in the context of the numerous other guidelines and manuscripts that are already available are discussed. ...
doi:10.1136/gut.2005.083600
pmid:16531521
pmcid:PMC1856188
fatcat:tohmiftxp5bjxjr7a2an6k5npq
Heyde Syndrome as aPresentation of Acquired Von WillebrandSyndrome: What theGastroenterologist Should Know
2022
Research Review
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In this document we will review the pathophysiological bases of the disease, its presentation and treatment options. ...
to the neck and back, without having, at that time, an explanation about the relationship between these two pathologies and assuming that the bleeding was generated by the presence of sclerotic vessels ...
Angiodysplasias can be found in any segment of the gastrointestinal tract and before the development of video capsule endoscopy (VCE) the most frequent site was thought to be the cecum and the ascending ...
doi:10.52845/jmrhs/2022-5-7-3
fatcat:6qn6bb7qijhc5njcwxq2to4ah4
Intestinal amyloidosis: Clinical manifestations and diagnostic challenge
2021
Advances in Clinical and Experimental Medicine
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The disease can easily be misdiagnosed with several other diseases of the digestive tract and lead to diagnostic challenges in clinical practice. ...
Amyloidosis is a heterogeneous group of diseases in which the extracellular deposition of abnormal fibrillar proteins disrupts tissue structure and function. ...
In some patients, push enteroscopy or capsule endoscopy are helpful to detect lesions that are limited to the jejunum. ...
doi:10.17219/acem/133521
pmid:33974753
fatcat:colyvj26p5g4jil4q7zu6llf4m
Gastroesophageal Reflux Disease: Medical or Surgical Treatment?
2009
Gastroenterology Research and Practice
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Diagnosis is based mainly on ambulatory esophageal pH testing and endoscopy. There has been a long-standing debate about the best treatment approach for this troublesome disease.Methods and Results. ...
The disease encompasses a broad spectrum of clinical symptoms and disorders from simple heartburn without esophagitis to erosive esophagitis with severe complications, such as esophageal strictures and ...
According to this report, GERD is a chronic disease but not progressive; reflux symptoms tend to recur but the endoscopic findings do not progress in most patients. ...
doi:10.1155/2009/371580
pmid:20069112
pmcid:PMC2804043
fatcat:gk3tfwrn5zbpbjqy3knfsyhfey
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