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Spatial patterns and functional profiles for discovering structure in fMRI data

Polina Golland, Danial Lashkari, Archana Venkataraman
2008 2008 42nd Asilomar Conference on Signals, Systems and Computers  
In both applications, our methods confirm previously known results in brain mapping and point to new research directions for exploratory analysis of fMRI data.  ...  We explore unsupervised, hypothesis-free methods for fMRI analysis in two different types of experiments. First, we employ clustering to identify large-scale functionally homogeneous systems.  ...  Spatial co-Activation Patterns in Diverse fMRI Data This study of functional connectivity included 7 subjects.  ... 
doi:10.1109/acssc.2008.5074650 pmid:26082607 pmcid:PMC4465961 fatcat:2sstrrvadzgqphxz6pd7erw7fi

Discovering Structure in the Space of Activation Profiles in fMRI [chapter]

Danial Lashkari, Ed Vul, Nancy Kanwisher, Polina Golland
2008 Lecture Notes in Computer Science  
We present a method for discovering patterns of activation observed through fMRI in experiments with multiple stimuli/tasks.  ...  Working in the space of activation profiles, we design a mixture model that finds the major activation patterns along with their localization maps and derive an algorithm for fitting the model to the fMRI  ...  This research was supported in part by NIH grants NIBIB NAMIC U54-EB005149, and NCRR NAC P41-RR13218, and by the NSF CA-REER grant 0642971.  ... 
doi:10.1007/978-3-540-85988-8_121 fatcat:smspyms5qrewzpwdxmcejetmsm

Nonparametric hierarchical Bayesian model for functional brain parcellation

Danial Lashkari, Ramesh Sridharan, Edward Vul, Po-Jang Hsieh, Nancy Kanwisher, Polina Golland
2010 2010 IEEE Computer Society Conference on Computer Vision and Pattern Recognition - Workshops  
We develop a method for unsupervised analysis of functional brain images that learns group-level patterns of functional response.  ...  Inference based on this model enables automatic discovery and characterization of salient and consistent patterns in functional signals.  ...  Acknowledgments This research was supported in part by the NSF IIS/CRCNS 0904625 grant, the NSF CAREER grant 0642971, the MIT McGovern Institute Neurotechnology Program, and the NIH NIBIB NAMIC U54-EB005149  ... 
doi:10.1109/cvprw.2010.5543434 pmid:21841977 pmcid:PMC3153957 dblp:conf/cvpr/LashkariSVHKG10 fatcat:qcjant7hqjfxpjfxhncutg2fmm

Discovering structure in the space of fMRI selectivity profiles

Danial Lashkari, Ed Vul, Nancy Kanwisher, Polina Golland
2010 NeuroImage  
We present a method for discovering patterns of selectivity in fMRI data for experiments with multiple stimuli/tasks.  ...  We introduce a representation of the data as profiles of selectivity using linear regression estimates, and employ mixture model density estimation to identify functional systems with distinct types of  ...  the pattern of discovered profiles and their maps.  ... 
doi:10.1016/j.neuroimage.2009.12.106 pmid:20053382 pmcid:PMC2976625 fatcat:ddaj3jtsyzepzkfr3gs3fwjeye

Adaptive integration of local region information to detect fine-scale brain activity patterns

ZongLei Zhen, Jie Tian, Hui Zhang
2008 Science in China Series E: Technological Sciences  
With the rapid development of functional magnetic resonance imaging (fMRI) technology, the spatial resolution of fMRI data is continuously growing.  ...  To improve the sensitivity of the activation detection, in this paper, multivariate statistical method and univariate statistical method are combined to discover the fine-grained activity patterns.  ...  Two GK with FWHM of 6 mm and 9 mm were used separately to smooth the data. There are two widely used GK in fMRI data analysis.  ... 
doi:10.1007/s11431-008-0124-7 fatcat:sn57ygvbxrcvdp7yzfuhhv63xe

Machine learning in resting-state fMRI analysis [article]

Meenakshi Khosla, Keith Jamison, Gia H. Ngo, Amy Kuceyeski, Mert R. Sabuncu
2018 arXiv   pre-print
Machine learning techniques have gained prominence for the analysis of resting-state functional Magnetic Resonance Imaging (rs-fMRI) data.  ...  Here, we present an overview of various unsupervised and supervised machine learning applications to rs-fMRI. We present a methodical taxonomy of machine learning methods in resting-state fMRI.  ...  Acknowledgements This work was supported by NIH R01 grants (R01LM012719 and R01AG053949), the NSF NeuroNex grant 1707312, and NSF CAREER grant (1748377).  ... 
arXiv:1812.11477v1 fatcat:nd6j5jbspzh2rmxyyufdyesxom

Exploratory fMRI analysis without spatial normalization

Danial Lashkari, Polina Golland
2009 Information processing in medical imaging : proceedings of the ... conference  
The method is based on a solely functional representation of the fMRI data and a hierarchical probabilistic model that accounts for both intersubject and intra-subject forms of variability in fMRI response  ...  We present an exploratory method for simultaneous parcellation of multisubject fMRI data into functionally coherent areas.  ...  Acknowledgments We thank Ed Vul and Nancy Kanwisher for providing us with the fMRI data.  ... 
pmid:19694280 pmcid:PMC2836541 fatcat:zaxet3edxzhhtoe6t3fh6tz22e

Exploratory fMRI Analysis without Spatial Normalization [chapter]

Danial Lashkari, Polina Golland
2009 Lecture Notes in Computer Science  
The method is based on a solely functional representation of the fMRI data and a hierarchical probabilistic model that accounts for both inter-subject and intra-subject forms of variability in fMRI response  ...  We present an exploratory method for simultaneous parcellation of multisubject fMRI data into functionally coherent areas.  ...  Acknowledgments We thank Ed Vul and Nancy Kanwisher for providing us with the fMRI data.  ... 
doi:10.1007/978-3-642-02498-6_33 fatcat:iz2t2gveq5batgfozozil6kphm

fMRI from EEG is only Deep Learning away: the use of interpretable DL to unravel EEG-fMRI relationships [article]

Alexander Kovalev, Ilia Mikheev, Alexei Ossadtchi
2022 arXiv   pre-print
Then, using the novel and theoretically justified weight interpretation methodology we recover individual spatial and time-frequency patterns of scalp EEG predictive of the hemodynamic signal in the subcortical  ...  The access to activity of subcortical structures offers unique opportunity for building intention dependent brain-computer interfaces, renders abundant options for exploring a broad range of cognitive  ...  Acknowledgment This work is supported by the Center for Bioelectric Interfaces NRU HSE, RF Government grant, AG. No. 075-15-2021-624  ... 
arXiv:2211.02024v2 fatcat:hp4cesfehratxewd34sfbfc6ym

Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks

Petra E. Vértes, Timothy Rittman, Kirstie J. Whitaker, Rafael Romero-Garcia, František Váša, Manfred G. Kitzbichler, Konrad Wagstyl, Peter Fonagy, Raymond J. Dolan, Peter B. Jones, Ian M. Goodyer, Edward T. Bullmore
2016 Philosophical Transactions of the Royal Society of London. Biological Sciences  
Here, we estimated intra-modular degree, inter-modular degree and connection distance for each of 285 cortical nodes in multi-echo fMRI data from 38 healthy adults.  ...  Nodes in superior and lateral cortex with high inter-modular degree and long connection distance had local transcriptional profiles enriched for oxidative metabolism and mitochondria, and for genes specific  ...  We thank Gita Prabu, Roger Tait, Cinly Ooi, John Suckling and Becky Inkster for fMRI data collection and storage.  ... 
doi:10.1098/rstb.2015.0362 pmid:27574314 pmcid:PMC5003862 fatcat:bwyqsyiibzdmtlwxi4eqflyr5e

Incorporating structured assumptions with probabilistic graphical models in fMRI data analysis [article]

Ming Bo Cai, Michael Shvartsman, Anqi Wu, Hejia Zhang, Xia Zhu
2020 arXiv   pre-print
We review a few recently developed algorithms in various domains of fMRI research: fMRI in naturalistic tasks, analyzing full-brain functional connectivity, pattern classification, inferring representational  ...  those assumptions and domain knowledge into probabilistic graphical models, and using those models to estimate properties of interest or latent structures in the data.  ...  Modeling structured residuals -Defining the problem: modeling spatiotemporal residuals in fMRI data fMRI data has structure in both the spatial and temporal dimension, and this spatiotemporal consistency  ... 
arXiv:2005.04879v1 fatcat:qsddwj7qi5gutk3vks3uf3rn2q

Search for patterns of functional specificity in the brain: A nonparametric hierarchical Bayesian model for group fMRI data

Danial Lashkari, Ramesh Sridharan, Edward Vul, Po-Jang Hsieh, Nancy Kanwisher, Polina Golland
2012 NeuroImage  
In this paper, we develop an algorithm that automatically learns patterns of functional specificity from fMRI data in a group of subjects.  ...  The discovered system activation profiles correspond to selectivity for a number of image categories such as faces, bodies, and scenes.  ...  Automatic detection of these profiles demonstrates the potential of our approach to discover novel patterns of specificity in the data.  ... 
doi:10.1016/j.neuroimage.2011.08.031 pmid:21884803 pmcid:PMC3972261 fatcat:dlkxqn4fizfobjgi56khpuja2u

Canonical Correlation Analysis for Feature-Based Fusion of Biomedical Imaging Modalities and Its Application to Detection of Associative Networks in Schizophrenia

Nicolle M. Correa, Yi-Ou Li, TÜlay Adali, Vince D. Calhoun
2008 IEEE Journal on Selected Topics in Signal Processing  
Typically data acquired through imaging techniques such as functional magnetic resonance imaging (fMRI), structural MRI (sMRI), and electroencephalography (EEG) are analyzed separately.  ...  As we show both with simulation results and application to real data, multimodal CCA (mCCA) proves to be a flexible and powerful method for discovering associations among various data types.  ...  The associate editor coordinating the review of this manuscript and approving it for publication was A. Cichocki. Dr.  ... 
doi:10.1109/jstsp.2008.2008265 pmid:19834573 pmcid:PMC2761661 fatcat:oenf7lffbvcv7ppvkflnwpa5bm

Representation Learning of Resting State fMRI with Variational Autoencoder [article]

Jung-Hoon Kim, Yizhen Zhang, Kuan Han, Minkyu Choi, Zhongming Liu
2020 bioRxiv   pre-print
Resting state functional magnetic resonance imaging (rs-fMRI) data exhibits complex but structured patterns. However, the underlying origins are unclear and entangled in rs-fMRI data.  ...  After being trained with large data from the Human Connectome Project, the model has learned to represent and generate patterns of cortical activity and connectivity using latent variables.  ...  Clustering in the latent space We encoded the rs-fMRI spatial pattern at every time point for 500 testing .  ... 
doi:10.1101/2020.06.16.155937 fatcat:bnuq7hcj3bdwtphu4vcthg4l6i

Spatiotemporal Trajectories in Resting-state FMRI Revealed by Convolutional Variational Autoencoder [article]

Xiaodi Zhang, Eric Maltbie, Shella Keilholz
2021 bioRxiv   pre-print
These spatiotemporal patterns provide insight into how activity flows across the brain in concordance with known network structures and functional connectivity gradients.  ...  patterns, independent component analysis, quasi-periodic patterns, and hidden Markov models.  ...  Aside from the spatial profiles, the functional connectivity of each latent variable's spatiotemporal pattern was calculated.  ... 
doi:10.1101/2021.01.25.427841 fatcat:kvrc5o2uwvebrc3na4bofp2c6m
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