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Physiological and geometrical effects in the upper airways with and without mandibular advance device for sleep apnea treatment
2020
Scientific Reports
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Fully describing the dynamic behavior of the airflow in this area is a severe challenge for the physicians. ...
In this paper we explore the dynamic behavior of airflow in the upper airways of 6 patients suffering obstructive sleep apnea with/without a mandibular advancement device using computational fluid dynamics ...
Schematic representation of the geometrical factor to characterize the pharynx.
Figure 4 . 4 Figure 4. Cross-sectional area of the minimum area for the 6 patients (with and without MAD) analyzed. ...
doi:10.1038/s41598-020-61467-4
pmid:32210246
fatcat:cq6shym6cjcdzajjbcmf5tkw3i
Awakening: Predicting external stimulation to force transitions between different brain states
2019
Proceedings of the National Academy of Sciences of the United States of America
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Specifically, we use a unique neuroimaging dataset of human sleep to systematically investigate where to stimulate the brain to force an awakening of the human sleeping brain and vice versa. ...
Given the biophysical limitations of direct electrical stimulation (DES) of microcircuits, this opens exciting possibilities for discovering stimulation targets and selecting connectivity patterns that ...
This allows for recurrent substates to be detected and characterized in terms of probability of occurrence and alternation profiles. ...
doi:10.1073/pnas.1905534116
pmid:31427539
pmcid:PMC6731634
fatcat:g7uzfih3h5hjvgq4boac6jqx7i
Usability, Acceptability, Feasibility, and Effectiveness of a Gamified Mobile Health Intervention (Triumf) for Pediatric Patients: Qualitative Study
2019
JMIR Serious Games
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Psychological support and mini games were the most often used components of the game, simultaneously the participants also highlighted the education module as one of the most preferred. ...
In addition, the study aimed to evaluate the preliminary effectiveness of the mobile health game. ...
We would like to acknowledge the contribution of Triumf Health team members who participated in the development of the digital health intervention involving Georgi Merdzhanov, Leandro Oscar Gil, Jose Manuel ...
doi:10.2196/13776
pmid:31573904
pmcid:PMC6792029
fatcat:jyhfatdnbrbolhz73vtmca3on4
Waking and dreaming consciousness: Neurobiological and functional considerations
2012
Progress in Neurobiology
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Acknowledgments AH is grateful for the support to the NIH, the NSF, and the John D. and Catherine T. Mac Arthur Foundation. KJF is funded by the Wellcome Trust. ...
We would like to thank Nicholas Tranquillo for help in preparing this manuscript. ...
We will see later that this loss of representational accuracy is completely understandable, because there are no visual prediction errors in sleep to constrain representations. ...
doi:10.1016/j.pneurobio.2012.05.003
pmid:22609044
pmcid:PMC3389346
fatcat:xvdzdhry45entfocese2ban3ry
Deep sleep and its cognitive effects - Slow wave activity and the learning and sleep cycle
2021
Zenodo
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Sleep is definitely an essential cerebral state for all living beings. The occurrence of sleep passed through the evolutionary sieve and is widespread in animal species. ...
In adults, sleep deprivation is detrimental for cognition and it is one of the worst tortures that can be inflicted. ...
Acknowledgment This work was carried out with support from the European Union Horizon 2020 ...
doi:10.5281/zenodo.5163097
fatcat:bpvpd4vkgnfwxpal4jsoz7rpqm
Comprehensive Analysis of N6-Methyladenosine Regulators in the Subcluster Classification and Drug Candidates Prediction of Severe Obstructive Sleep Apnea
2022
Frontiers in Genetics
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Obstructive sleep apnea (OSA) is the most common type of sleep apnea that impacts the development or progression of many other disorders. ...
And then, we explored the character of immune microenvironment, molecular functionals, protein-protein interaction networks and miRNA-TF coregulatory networks for each subcluster. ...
PPIs were exported from the STRING database and then entered into Cytoscape for a better visual representation and analysis of hub genes. ...
doi:10.3389/fgene.2022.862972
pmid:35559050
pmcid:PMC9086428
fatcat:5iky7oc5m5ekfkcyrg74iqgq7i
A refined model of sleep and the time course of memory formation
2005
Behavioral and Brain Sciences
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Research in the neurosciences continues to provide evidence that sleep plays a role in the processes of learning and memory. ...
In contrast, the consolidation stage, resulting in additional/enhanced learning in the absence of further rehearsal, does appear to rely on the process of sleep, with evidence for specific sleep-stage ...
This work was supported by the National Science Foundation (BCS-0121953) and the National Institute of Health (MH-48832 and DA11744-01A1). ...
pmid:16047457
fatcat:nzcbcc5orjavpl4fwni7kppcs4
Waking and Dreaming Consciousness: Neurobiological and Functional Considerations
[chapter]
2018
Reference Module in Neuroscience and Biobehavioral Psychology
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The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. ...
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. ...
Acknowledgments AH is grateful for the support to the NIH, the NSF, and the John D. and Catherine T. Mac Arthur Foundation. KJF is funded by the Wellcome Trust. ...
doi:10.1016/b978-0-12-809324-5.21972-x
fatcat:bn5kxuhorvgafgairaynradusu
Where is the classic interference theory for sleep and memory?
2005
Behavioral and Brain Sciences
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This work was supported by the National Science Foundation (BCS-0121953) and the National Institute of Health (MH-48832 and DA11744-01A1). ...
This work was supported by the National Institute of Health (MH-69935, MH-48832, MH-69935 and DA11744-01A1) and the National Science Foundation (BCS-0121953). ...
Therefore, to maintain the ability for continued memory formation, the adult cortex must, by necessity, continually modify its central representations in a dynamic balancing act to ensure that the most ...
doi:10.1017/s0140525x05250021
fatcat:tgui2trb2vbxdoz767nhdi45si
Cardiovascular prevention in women
2019
Journal of Cardiovascular Medicine
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It is very difficult to understand whereas obstructive sleep apnea in women is independently associated with hypertension or if many confounders acting at different stages of the woman lifespan mediate ...
Despite the lower prevalence of type 2 diabetes, years of life lost owing to the disease for women are substantially higher compared with men. ...
Acknowledgements The Italian Society of Cardiology
Conflicts of interest None declared ...
doi:10.2459/jcm.0000000000000831
pmid:31246698
fatcat:qcwutiopmfho3hm4e3lfokv6ea
Robust Long-Range Coordination of Spontaneous Neural Activity in Waking, Sleep and Anesthesia
2014
Cerebral Cortex
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methods for unbiased extraction of network information from these data. ...
In part, this lack in understanding owes to the invasiveness of electrophysiological acquisition, the difficulty in their simultaneous recording over large cortical areas, and the absence of fully established ...
Notes The authors appreciate Dr. Picchioni for helpful discussion on sleep electrophysiology and Dr. Hutchison for his help on fMRI results presentation. Conflict of Interest: None declared. ...
doi:10.1093/cercor/bhu089
pmid:24812083
pmcid:PMC4537437
fatcat:toyf4kevbvgntp3tkdgeribgou
Integrating User Affective State Assessment in Enhancing HCI: Review and Proposition
2008
Open Cybernetics and Systemics Journal
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A user affective state assessment framework developed by the author based on dynamic Bayesian networks is also visited. ...
A survey of the state-of-the-art of affective state assessment focuses on computational assessment models underlying different studies. ...
In our research, we will focus on the first three modules for sleep regulation, detection and understanding/performance assessment functions. ...
doi:10.2174/1874110x00802010192
fatcat:nlauknghefekrfjmxxkwvsnnfi
Harnessing the Web for Population-Scale Physiological Sensing
2017
Proceedings of the 26th International Conference on World Wide Web - WWW '17
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last for a period of six days. ...
This work demonstrates the feasibility of using online interactions for large-scale physiological sensing. ...
Interaction patterns of different devices and applications have been studied on small scale to better understand mobile device usage [12] , to detect stress [43] , used as biometric signals for authentication ...
doi:10.1145/3038912.3052637
dblp:conf/www/AlthoffHWZ17
fatcat:j6xhxacvevcs5gfhuh5s6u5tqi
Harnessing the Web for Population-Scale Physiological Sensing: A Case Study of Sleep and Performance
[article]
2017
arXiv
pre-print
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last for a period of six days. ...
This work demonstrates the feasibility of using online interactions for large-scale physiological sensing. ...
We thank Jure Leskovec, Emma Pierson, Marinka Zitnik, David Hallac, David Jurgens and the anonymous reviewers for their valuable feedback on the manuscript. ...
arXiv:1701.07083v2
fatcat:wrrqap4y5fgwtkctfhvrnrcdry
Features of Circadian Rhythms in Patients with Cerebrovascular Diseases
[chapter]
2018
Circadian Rhythm - Cellular and Molecular Mechanisms
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The effectiveness of melatonin for the normalization of sleep and CR in patients with insomnia, acute stroke, depressive disorders is shown. ...
Complex therapy of the patients with CVD taking into account chronobiological disorders allows to eliminate the adverse effect of sleep disorders and CR on the regulation of the cardiovascular system and ...
Acknowledgements We thank Dmitry Petrov for his assistance in translation of the text. We wish to acknowledge the patients who participated in our studies. ...
doi:10.5772/intechopen.75963
fatcat:eqyjhdjvwzb23d2qxy4jmzfw7e
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