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How to Improve Divergent Thinking Capability by Information Technology and Extenics
2014
Procedia Computer Science
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Divergent Thinking capability has become increasingly important for innovation and problem solving. We need efficient and effective ways to support the divergent thinking process. Based on Basic-element theory of Extenics, a new model to improve the divergent thinking capability has been developed using information management and extension transformation. With the guide of the extension innovation method, we collect attributes of different things through information technology on the web, and
doi:10.1016/j.procs.2014.05.256
fatcat:kro3aik6pfbatd2nzgpow36yy4
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... en extend many divergent thinking directions systematically. The case study shows it is helpful as a common innovative approach to improve divergent thinking capability by integration of information technology and Extenics.
Enhancing hydrogen production from the pyrolysis-gasification of biomass by size-confined Ni catalysts on acidic MCM-41 supports
2018
Catalysis Today
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surface inside nanopores; 2) enhance the support and Ni interaction for better reduction property and surface activity of Ni nanoparticles and improve the reforming performance. ...
For minimizing the influence of the Ni particle size for the biomass gasification, the uniform Ni nanoparticles around 2-3 nm were loaded into one type of mesoporous support MCM-41 with various acidity ...
Figure 1 : 1 Small angel XRD pattern of Ni catalysts on Ni/H-[Al] MCM-41, Ni/Na-[Si] MCM-41 and Ni/H-[Si] MCM-41 supports.For the XRD patterns for Ni/MCM-41 catalysts in the range of 2 between 10-70°, ...
doi:10.1016/j.cattod.2017.05.077
fatcat:zije67n6v5aghckxw2bm7l3ty4
Risk Factors Affecting Muscle Mass Decline in Maintenance Hemodialysis Patients
2022
BioMed Research International
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Objective. There is a high prevalence of sarcopenia in maintenance hemodialysis (MHD) patients, which is known to be associated with increased mortality. This study is aimed at analyzing the risk factors affecting muscle mass decline in MHD patients. Methods. This retrospective study included MHD patients who underwent two body composition assessments in October 2013 and November 2017. Depending on whether there was muscle loss or not, the patients were divided into a normal muscle mass (NMM)
doi:10.1155/2022/2925216
pmid:36582602
pmcid:PMC9794426
fatcat:vql6u2npurg3zin33tdaazvaoe
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... oup and a muscle mass decline (MMD) group. According to the muscle mass decline rate, patients in the MMD group were further classified into a low-rate group and a high-rate group. Biochemical variables, serum vitamin concentrations, anthropometric data, SGA, muscle mass, handgrip, and daily steps were assessed. Risk factors for muscle mass decline were screened by multivariate logistic analysis and linear regression analysis. Results. Of the 72 MHD patients included in this study, 33 were male and 39 were female with a mean age of 56.80 ± 10.86 years and a mean dialysis duration of 7.50 ± 5.20 years. Age ( P = .014 ) and serum 25(OH)D ( P = .040 ) were found to be associated with a higher risk of muscle mass decline after adjusting for gender, dialysis vintage, albumin, and hs-CRP ( P = .040 ). Further analysis found that dialysis vintage ( β = 0.285 , P = .030 ), 25(OH)D ( β = − 0.351 , P = .007 ), and log NT-proBNP ( β = 0.312 , P = .020 ) were risk factors associated with the muscle mass decline rate in MHD patients. Conclusion. Age and serum 25(OH)D were associated with a higher risk of muscle mass decline, while 25(OH)D, dialysis vintage, and NT-proBNP were associated with the muscle mass decline rate in MHD patients.
LINC02476 Promotes the Malignant Phenotype of Hepatocellular Carcinoma by Sponging miR-497 and Increasing HMGA2 Expression
2020
OncoTargets and Therapy
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Long noncoding RNAs (lncRNAs) can promote hepatocellular carcinoma (HCC) initiation and progression. In this report, we examined the role of lncRNA LINC02476 in HCC. The expression levels of different lncRNAs in HCC were explored using the TCGA database and lncRNA LINC02476 was selected for further study. The expression of LINC02476 in HCC tissues was determined by real-time PCR. The clinicopathological characteristics of HCC patients were analyzed relative to the expression of LINC02476. The
doi:10.2147/ott.s237069
pmid:32280244
pmcid:PMC7132004
fatcat:ety7fqaafjdc3nnnex56ty4z2q
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... pression of LINC02476 was downregulated in HCC cells using a lentiviral vector and different assays were performed to study cell growth, proliferation, invasion, apoptosis and the cell cycle. MiR-497 was selected as a miRNA that could interact with LINC02476 which was further tested by RNA immunoprecipitation. HMGA2 was selected as a possible target of miR-497, and their interaction was examined by a luciferase reporter assay. LINC02476 expression was elevated in HCC cell lines and HCC tissues. When LINC02476 was downregulated, the growth and the invasion of HCC cells decreased in vitro and in vivo. LINC02476 negatively regulated the expression of miR-497 by acting as a ceRNA. HMGA2 was directly targeted and inhibited by miR-497. The results indicate that LINC02476 functions through the miR-497/HMGA2 axis and that it has a role in the growth and metastasis of HCC cells. Therefore, LINC02476 could be an interesting new molecular target in HCC therapies.
A Practical Electronic Health Record-based Dry Weight Supervision Model for Hemodialysis Patients
2019
IEEE Journal of Translational Engineering in Health and Medicine
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Objective: Dry Weight (DW) is a typical hemodialysis (HD) prescription for End-Stage Renal Disease (ESRD) patients. However, an accurate DW assessment is difficult due to the complication of body components and individual variations. Our objective is to model a clinically practicable DW estimator. Method: We proposed a time series-based regression method to evaluate the weight fluctuation of HD patients according to Electronic Health Record (EHR). A total of 34 patients with 5100 HD sessions
doi:10.1109/jtehm.2019.2948604
pmid:32309061
pmcid:PMC6850034
fatcat:adu23zbwifh6hhiydiaukrmu54
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... a were selected and partitioned into three groups; in HD-stabilized, HD-intolerant, and near-death. Each group's most recent 150 HD sessions data were adopted to evaluate the proposed model. Results: Within a 0.5 kg absolute error margin, our model achieved 95.44%, 91.95%, and 83.12% post-dialysis weight prediction accuracies for the HD-stabilized, HD-intolerant, and near-death groups, respectively. Within a 1%relative error margin, the proposed method achieved 97.99%, 95.36%, and 66.38% accuracies. For HD-stabilized patients, the Mean Absolute Error (MAE) of the proposed method was 0.17 kg ± 0.04 kg. In the model comparison experiment, the performance test showed that the quality of the proposed model was superior to those of the state-of-the-art models. Conclusion: The outcome of this research indicates that the proposed model could potentially automate the clinical weight management for HD patients. Clinical Impact: This work can aid physicians to monitor and estimate DW. It can also be a health risk indicator for HD patients.
Manipulation of lignin metabolism by plant densities and its relationship with lodging resistance in wheat
2017
Scientific Reports
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Increasing plant density is one of the most efficient ways of increasing wheat (Triticum aestivum L.) grain production. However, overly dense plant populations have an increased risk of lodging. We examined lignin deposition during wheat stem development and the regulatory effects of plant density using the wheat cultivars shannong23 and weimai8. Plants were cultivated at densities of 75, 225 and 375 plants per m 2 during two growing seasons. Our results showed that decreasing plant density
doi:10.1038/srep41805
pmid:28150816
pmcid:PMC5288770
fatcat:k3vt3xzsrjgd3o7zdsbwh3u7fi
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... nced culm quality, as revealed by increased culm diameter, wall thickness and dry weight per unit length, and improved the structure of sclerenchyma and vascular bundles by increasing lignification. In addition, more lignins were deposited in the secondary cell walls, resulting in strong lodging resistance. The guaiacyl unit was the major component of lignin and there was a higher content of the syringyl unit than that of the hydroxybenzyl unit. Furthermore, we hypothesised that the syringyl unit may correlate with stem stiffness. We describe here, to the best of our knowledge, the systematic study of the mechanism involved in the regulation of stem breaking strength by plant density, particularly the effect of plant density on lignin biosynthesis and its relationship with lodging resistance in wheat.
Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study
2020
Clinical Interventions in Aging
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Reduced kidney function has been associated with an increased risk for adverse outcomes. Accurate assessment of glomerular filtration rate (GFR) is key to diagnosis and management of kidney disfunction. Debate exists on the best GFR estimation equation for elderly people. This study aimed to compare the predictive validity and discriminative ability of four GFR equations in relation to 2-year and 6-year mortality in exceptional longevity (EL) (those over 95 years old with intact health)
doi:10.2147/cia.s250535
pmid:32546991
pmcid:PMC7266309
fatcat:r36wb6oacraardjj2lff7e4z64
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... als and is an ideal model to address factors relating to life span and age-related diseases. This study used 6 years' data of 278 EL from the Rugao longevity cohort. Baseline GFR was estimated using four equations: Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, Modification of Diet in Renal Disease Study (MDRD) equation, Berlin Initiative Study-1 (BIS) equation, and modified MDRD equation. Predictive validity was tested using Cox proportional hazards analysis. Overall improvement in reclassification based on estimated GFR (eGFR) was assessed applying net reclassification improvement (NRI). Mean age of participants was 97±2 years with median follow-up of 2.6 years. Median (IQR) eGFR by CKD-EPI, MDRD, BIS, and modified MDRD equations were 73.9 (62.2-77.6), 82.3 (67.4-98.6), 56.4 (47.9-63.9), and 101.5 (83.1-121.6) mL/min per 1.73 m2, respectively. Higher eGFREPI was associated with lower mortality after multivariate adjustment (for continuous eGFREPI, HRtwo-year 1.018, 95% CI 1.002-1.033, P=0.023; HRsix-year 1.013, 95% CI 1.002-1.025, P=0.022), while eGFR from other equations did not show any associations with mortality. NRI for two-year mortality was 0.14 and approximately significant, which may favor the CKD-EPI when compared to BIS equation (P=0.052). The CKD-EPI equation showed more accurate estimation of kidney function in the elderly with respect to GFR distribution and predictability of mortality risk.
HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population
2017
Scientific Reports
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Previously, we have identified single nucleotide polymorphisms (SNPs) rs7958904 and rs4759314 in long non-coding RNA HOX transcript antisense RNA (HOTAIR) were significantly associated with risk of colorectal and gastric cancer, respectively. Here, we aimed to investigate the association between HOTAIR SNPs and cervical cancer (CC) susceptibility. A total of 1209 cases and 1348 controls were enrolled for association study and genotyped with TaqMan allelic discrimination method. The Cancer
doi:10.1038/s41598-017-03174-1
pmid:28600545
pmcid:PMC5466640
fatcat:jlevdpmqmrbcxat6t4fv4tjp6q
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... Atlas (TCGA) database was utilized for in vivo analysis of allele-specific HOTAIR expression. MTT assay was employed for evaluation of allele-specific cell proliferation. The rs7958904 CC genotype was related to an increased risk of cervical cancer compared with the GG/GC genotypes (OR = 1.57, 95% CI = 1.10-2.25). TCGA database showed the CC tissues with rs7958904 CC genotype had higher HOTAIR expression than those with GG genotype (P = 0.046). MTT assay demonstrated a growth-promoting role of rs7958904 C allele on CC cells. Further functional studies on the effect of rs7958904 on biological behavior of CC cells are needed to confirm and extend our findings. In conclusion, HOTAIR rs7958904 might influence CC susceptibility through modulation of CC cell proliferation, and could serve as a diagnostic biomarker. Cervical cancer (CC) is one of the most common causes of cancer mortality for women worldwide. According to the International Agency for Research on Cancer (IARC) (GLOBOCAN 2012), an estimated of 266,000 deaths from CC occurred worldwide in 2012, accounting for 7.5% of all female cancer deaths 1 . Although infection with high risk human papillomavirus (HR-HPV) has been accepted as the major risk factor of CC, individual genetic heritability also plays a fundamental role in the development of CC 2-4 . Long noncoding RNAs (lncRNAs) are a kind of non-coding RNAs longer than 200 nucleotides 5, 6 . The ENCODE project suggests that about 76% of the human genome is transcribed to a series of lncRNAs 7 . Recently, lncRNAs have gained more and more attention due to their complex and extensive regulatory functions 5, 6, 8 . LncRNAs functions vitally in a broad range of cellular processes, such as cell growth, survival, migration and invasion 9, 10 . Deregulated lncRNAs have been reported to be involved in pathogenesis of cancers 6, 11 . LncRNA HOX transcript antisense intergenic RNA (HOTAIR) locates in the HOXC locus, and involves epigenetic regulation of transcription in a 40 kb region of HOXD 10 . HOTAIR participates in the development and progression of Published: xx xx xxxx OPEN www.nature.com/scientificreports/ 2 Scientific RepoRts | 7: 3144 |
Plant Density Effect on Grain Number and Weight of Two Winter Wheat Cultivars at Different Spikelet and Grain Positions
2016
PLoS ONE
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In winter wheat, grain development is asynchronous. The grain number and grain weight vary significantly at different spikelet and grain positions among wheat cultivars grown at different plant densities. In this study, two winter wheat (Triticum aestivum L.) cultivars, 'Wen-nong6' and 'Jimai20', were grown under four different plant densities for two seasons, in order to study the effect of plant density on the grain number and grain weight at different spikelet and grain positions. The
doi:10.1371/journal.pone.0155351
pmid:27171343
pmcid:PMC4865215
fatcat:yv4m4bv6mrgvhdejr2gb2fqsma
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... showed that the effects of spikelet and grain positions on grain weight varied with the grain number of spikelets. In both cultivars, the singlegrain weight of the basal and middle two-grain spikelets was higher at the 2 nd grain position than that at the 1 st grain position, while the opposite occurred in the top two-grain spikelets. In the three-grain spikelets, the distribution of the single-grain weight was different between cultivars. In the four-grain spikelets of Wennong6, the single-grain weight was the highest at the 2 nd grain position, followed by the 1 st , 3 rd , and 4 th grain positions. Regardless of the spikelet and grain positions, the single-grain weight was the highest at the 1 st and 2 nd grain positions and the lowest at the 3 rd and 4 th grain positions. Overall, plant density affected the yield by controlling the seed-setting characteristics of the tiller spike. Therefore, wheat yield can be increased by decreasing the sterile basal and top spikelets and enhancing the grain weight at the 3 rd and 4 th grain positions, while maintaining it at the 1 st and 2 nd grain positions on the spikelet. 3 / 15 **Significant at P < 0.01. D1, 75 plants m -2 ; D2, 225 plants m -2 ; D3, 375 plants m -2 ; D4, 525 plants m -2 .
Early Renal-Replacement Therapy May Reduce the All-Cause Mortality of Severe COVID-19: An Observational Cohort Study
2022
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Qian/Wang/You/Luo/Li/Chen/Chen/Li/ Wang/Zhang/Yuan/Ni/Chen Blood Purif
Results
Demographic and Clinical Characteristics of the Study Cohort The mean age of the 58 participants was 68.4 ± 14.6 years ...
Qian/Wang/You/Luo/Li/Chen/Chen/Li/ Wang/Zhang/Yuan/Ni/Chen Blood Purif 8 DOI: 10.1159/000524229
Table 1 . 1 Baseline demographic and clinical characteristics of the study cohort before ICU admission ...
Li Ni, Weichen Zhang, and Kangjie Wang collected and recorded the clinical and laboratory data. Mengjing Wang, Janfeng Luo, and Jing Qian analyzed data and performed statistical analysis. ...
doi:10.1159/000524229
pmid:35526521
pmcid:PMC9148880
fatcat:rg65w4y54vbghaesiudfzhyz74
Contents list
2024
Inorganic Chemistry Frontiers
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moieties boost the hydrogen evolution reaction by optimizing H absorption Shuang Ma, Peiying Yang, Jin Chang, Heng Zhang,* Mengjing Li, Siqi Zhang, Jiafang Liu,* Fanghan Wang, Chuan Cheng, Ao Zhou and ...
through the incorporation of YSb nanoprecipitates Dandan Qin,* Wenjing Shi, Xin Wang, Cunlei Zou, Chun Shang, Xiangcheng Cui, Huijun Kang, Yunzhuo Lu* and Jiehe Sui* 1733 High-density accessible Ru-Se-Ni ...
doi:10.1039/d4qi90018a
fatcat:s4ceuwueareelpn7t74xrwh77a
Effect of adding yttrium on precipitation behaviors of inclusions in E690 ultra high strength offshore platform steel
2020
High Temperature Materials and Processes
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affinity toward O and S and react with these elements to form spindle and spherical RE x O y , RE x S y , and RE x O y S z inclusions, thus avoiding the anisotropy of Xiaojun Xi, Shaoying Li, Jingshe Li, Mengjing ...
C
Si
Mn P
S
O
Al
Nb
V
Ti
Ni
Cr
Cu
Mo
Y
In No. 1 test steel, namely, the steel without addition of yttrium, MnS, and Al 2 O 3 are the dominating inclusions. ...
doi:10.1515/htmp-2020-0089
fatcat:wjxjtnnxtvexjp6grf6dmin2im
Distribution and assessment of heavy metals in the surface sediment of Yellow River, China
2016
Journal of Environmental Sciences(China)
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The concentrations of the studied heavy metals followed the order: Zn > Cr > Cu > Ni > Pb > As > Cd. Nearly 50% of sites had Cu and Cr accumulation. ...
Contents of Zn, Pb, Ni, Cu, Cr, Cd, As were measured, and the pollution status was assessed using three widely used pollution assessment methods, including the single factor index method, Nemerow pollution ...
The mean E r i for seven heavy metals decreased in the order Cd > Cu > Ni > Pb > As > Cr > Zn. ...
doi:10.1016/j.jes.2015.10.017
pmid:26899643
fatcat:rsmu7mzhtjdd7kmqkmopb6y6wm
The influence of the media on children's language
2022
Technium Social Sciences Journal
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"pes plus ni barabart me gjasht (5 + 1 = 6)" or nizet plus gjasht barabart me nizet e gjasht (20+6=26). ...
will no longer they said bastan but shalqin (watermelon), they would not say patlixhan but domate (eggplant) they would not say kumpir but patate (potatoes), penxhere but dritare (window), sabah but mëngjes ...
doi:10.47577/tssj.v36i1.7501
fatcat:pnntaypzlvgmbee2sixmonatnu
Self-consistent relativistic quasiparticle random-phase approximation and its applications to charge-exchange excitations
2017
Physical Review C
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Large discrepancies are found for the Ni, Zn, and Ge isotopes with neutron number smaller than 50, as well as the Sn isotopes with neutron number smaller than 82. ...
Although the measurement of charge-exchange excitations has achieved great progress in recent years, their theoretical studies * haozhao.liang@riken.jp † mengj@pku.edu.cn are still essential to understand ...
Deviations of the theoretical nuclear masses from the experimental data [82] for the even-even Ca, Ni, and Sn isotopes. ...
doi:10.1103/physrevc.95.044301
fatcat:uoe5f42bpng6tlov77w6k4xktu
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