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AI-Enabled Lung Cancer Prognosis [article]

Mahtab Darvish, Ryan Trask, Patrick Tallon, Mélina Khansari, Lei Ren, Michelle Hershman, Bardia Yousefi
2024 arXiv   pre-print
Among these, Non-Small Cell Lung Cancer (NSCLC) is the predominant subtype, characterized by a notably bleak prognosis and low overall survival rate of approximately 25% over five years across all disease  ...  Recent advancements in artificial intelligence (AI) have revolutionized the landscape of lung cancer prognosis.  ...  The imaging-based applications of deep neural networks showed significant improvements in all aspects of lung cancer prognosis.  ... 
arXiv:2402.09476v1 fatcat:atoy3fej2rgu3n72et3dq2fpom

Deep Learning Model as a New Trend in Computer-aided Diagnosis of Tumor Pathology for Lung Cancer

Lei Cong, Wanbing Feng, Zhigang Yao, Xiaoming Zhou, Wei Xiao
2020 Journal of Cancer  
In this review, we will introduce the application, progress and problems of deep learning in pathology of lung cancer and make prospects for its future development.  ...  Lung cancer is one of the main causes of cancer-related death in the world.  ...  Zhenxiang Chen, Vice Dean of College of Information Science and Engineering, Jinan University, for his excellent suggestion and assist work for this manuscript.  ... 
doi:10.7150/jca.43268 pmid:32284758 pmcid:PMC7150458 fatcat:5lq3sjp2z5ecbomw43ab5howzy

A narrative review of artificial intelligence-assisted histopathologic diagnosis and decision-making for non-small cell lung cancer: achievements and limitations

Yongzhong Li, Donglai Chen, Xuejie Wu, Wentao Yang, Yongbing Chen
2021 Journal of Thoracic Disease  
More advanced deep learning for classifying pathologic images with minimal human interactions has been developed in addition to the conventional machine learning scheme.  ...  Lung cancer is one of the most common cancers and the leading cause of cancer-related deaths worldwide.  ...  carcinoma; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; ASC, adenosquamous carcinoma; LC, large cell lung cancer  ... 
doi:10.21037/jtd-21-806 pmid:35070383 pmcid:PMC8743410 fatcat:k6mnyzlvxnfyhlmd7d2b2hsixe

Artificial intelligence-assisted decision making for prognosis and drug efficacy prediction in lung cancer patients: a narrative review

Jingwei Li, Jiayang Wu, Zhehao Zhao, Qiran Zhang, Jun Shao, Chengdi Wang, Zhixin Qiu, Weimin Li
2021 Journal of Thoracic Disease  
These models have the potential to assist radiologists and oncologists in detecting lung cancer, predicting prognosis and developing personalized treatment plans for better outcomes of the patients.  ...  AI, especially for those based on deep learning and radiomics, is capable of assisting clinical decision making from many aspects, for its quantitatively interpretation of patients' information and its  ...  According to its histological classification, lung cancer consists of smallcell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) (1) .  ... 
doi:10.21037/jtd-21-864 pmid:35070384 pmcid:PMC8743400 fatcat:lrkxluf6zjh3daww2yu5htvfbe

Deep learning in cancer diagnosis, prognosis and treatment selection

Khoa A. Tran, Olga Kondrashova, Andrew Bradley, Elizabeth D. Williams, John V. Pearson, Nicola Waddell
2021 Genome Medicine  
We provide specific examples of how deep learning may be applied in cancer diagnosis, prognosis and treatment management.  ...  We focus on the deep learning applications for omics data types, including genomic, methylation and transcriptomic data, as well as histopathology-based genomic inference, and provide perspectives on how  ...  Acknowledgements Khoa Tran was the recipient of the Maureen and Barry Stevenson PhD Scholarship, we are grateful to Maureen Stevenson for her support.  ... 
doi:10.1186/s13073-021-00968-x pmid:34579788 pmcid:PMC8477474 fatcat:y73fumwdazft3pw47gqdcncnue

Artificial Intelligence in Cancer Research and Precision Medicine

Bhavneet Bhinder, Coryandar Gilvary, Neel S. Madhukar, Olivier Elemento
2021 Cancer Discovery  
Availability of high-dimensionality datasets coupled with advances in high-performance computing, as well as innovative deep learning architectures, has led to an explosion of AI use in various aspects  ...  These applications range from detection and classification of cancer, to molecular characterization of tumors and their microenvironment, to drug discovery and repurposing, to predicting treatment outcomes  ...  Elemento is supported by NIH grants UL1TR002384 and R01CA194547, and the Leukemia and Lymphoma Society Specialized Center of Research grants 180078-02 and 7021-20.  ... 
doi:10.1158/2159-8290.cd-21-0090 pmid:33811123 pmcid:PMC8034385 fatcat:x42n62qmrva2zodrxj4tf7bveq

Deep Learning Approaches in Histopathology

Alhassan Ali Ahmed, Mohamed Abouzid, Elżbieta Kaczmarek
2022 Cancers  
The revolution of artificial intelligence and its impacts on our daily life has led to tremendous interest in the field and its related subtypes: machine learning and deep learning.  ...  Scientists and developers have designed machine learning- and deep learning-based algorithms to perform various tasks related to tumor pathologies, such as tumor detection, classification, grading with  ...  Acknowledgments: Alhassan Ali Ahmed and Mohamed Abouzid are participants of the STER Internationalization of Doctoral Schools Program from NAWA Polish National Agency for Academic Exchange No.  ... 
doi:10.3390/cancers14215264 pmid:36358683 pmcid:PMC9654172 fatcat:a5j6te3zifgsrmrdxjz76rvxw4

The future of artificial intelligence in thoracic surgery for non-small cell lung cancer treatment a narrative review

Namariq Abbaker, Fabrizio Minervini, Angelo Guttadauro, Piergiorgio Solli, Ugo Cioffi, Marco Scarci
2024 Frontiers in Oncology  
ObjectivesTo present a comprehensive review of the current state of artificial intelligence (AI) applications in lung cancer management, spanning the preoperative, intraoperative, and postoperative phases.MethodsA  ...  AI holds promise in managing lung cancer, challenges exist.  ...  in early-stage non-small-cell lung cancer.  ... 
doi:10.3389/fonc.2024.1347464 pmid:38414748 pmcid:PMC10897973 fatcat:qemjpd232zfhzglgv6zmzan6kq

Advances in artificial intelligence to predict cancer immunotherapy efficacy

Jindong Xie, Xiyuan Luo, Xinpei Deng, Yuhui Tang, Wenwen Tian, Hui Cheng, Junsheng Zhang, Yutian Zou, Zhixing Guo, Xiaoming Xie
2023 Frontiers in Immunology  
This article focuses on the current prediction models based on information from histopathological slides, imaging-omics, genomics, and proteomics, and reviews their research progress and applications.  ...  early implementation of AI-assisted diagnosis and treatment systems in the future.  ...  All the figures in this article are made by Figdraw (www.figdraw.com) and Biorender (biorender.com).  ... 
doi:10.3389/fimmu.2022.1076883 pmid:36685496 pmcid:PMC9845588 fatcat:7pz4kvdsjjejjkv4de3yjjvqvi

The current issues and future perspective of artificial intelligence for developing new treatment strategy in non-small cell lung cancer: harmonization of molecular cancer biology and artificial intelligence

Ichidai Tanaka, Taiki Furukawa, Masahiro Morise
2021 Cancer Cell International  
of personalized medicine in non-small lung cancer.  ...  The use of AI, such as machine learning approaches and deep learning systems, allows for the efficient analysis of massive omics data combined with accurate clinical information and can lead to comprehensive  ...  in non-small-cell lung cancer.  ... 
doi:10.1186/s12935-021-02165-7 pmid:34446006 pmcid:PMC8393743 fatcat:ksvydxnfnnehfno2qbtdeagcgm

Editorial: RNA Modification in Human Cancers: Roles and Therapeutic Implications

You Zhou, Tao Huang, Tianbao Li, Jing Sun
2022 Frontiers in Genetics  
Lu et al. uncovered that miR-27a-3p modulated ferroptosis via targeting SLC7A11 in non-small cell lung cancer cells, implying the importance of miR-27a-3p/SLC7A11 in ferroptosis.  ...  Accumulating research has witnessed the high frequency of m 6 A modification in cancers which could be used to predict diagnosis and prognosis of cancer patients (Chen et al., 2018) .  ...  Yang et al. developed a deep convolutional neural network-based framework to evaluate efficacy of immunological therapy for lung cancer from histopathological images.  ... 
doi:10.3389/fgene.2022.845744 pmid:35173771 pmcid:PMC8841760 fatcat:pq65diwyfndjnovhhi2m6jwy4u

Artificial Intelligence to Decode Cancer Mechanism: Beyond Patient Stratification for Precision Oncology

Sandip Kumar Patel, Bhawana George, Vineeta Rai
2020 Frontiers in Pharmacology  
of diagnostic and prognostic markers, and (d) monitor patient's response to drugs/treatments and recovery.  ...  Cancer is a major cause of death worldwide, accounting for an estimated 9.6 million deaths in 2018.  ...  MSI tool was used to identify unique region-of-interest-specific biomarkers (lipid signature) and therapeutic targets to classify colorectal cancer and subtyping in non-small cell lung cancer (Kriegsmann  ... 
doi:10.3389/fphar.2020.01177 pmid:32903628 pmcid:PMC7438594 fatcat:u7mdynhnwfazbn6jhvcagorp2a

What can artificial intelligence teach us about the molecular mechanisms underlying disease?

Gary J. R. Cook, Vicky Goh
2019 European Journal of Nuclear Medicine and Molecular Imaging  
Non-small-cell lung cancer is used as an exemplar and the focus of this review as the most common tumour type in which AI and ML approaches have been tested and to illustrate some of the concepts.  ...  in machine learning (ML).  ...  , and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.  ... 
doi:10.1007/s00259-019-04370-z pmid:31190176 pmcid:PMC6879441 fatcat:q57b7kjlwzd7lnwcpp3iu7zbre

Deep Learning of Histopathology Images at the Single Cell Level

Kyubum Lee, John H. Lockhart, Mengyu Xie, Ritu Chaudhary, Robbert J. C. Slebos, Elsa R. Flores, Christine H. Chung, Aik Choon Tan
2021 Frontiers in Artificial Intelligence  
The spatial organization of these different cell types in TIME could be used as biomarkers for predicting drug responses, prognosis and metastasis.  ...  Recently, deep learning approaches have been widely used for digital histopathology images for cancer diagnoses and prognoses.  ...  The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders.  ... 
doi:10.3389/frai.2021.754641 pmid:34568816 pmcid:PMC8461055 fatcat:utnyq2nvmzbitkipjo6tpiuioq

In the literature: October 2020

Valentina Gambardella, Gema Bruixola, Clara Alfaro, Andrés Cervantes
2020 ESMO Open  
board or speaker fees from Merck Serono, Roche, Servier, Takeda and Astellas in the last 5 years.  ...  Provenance and peer review Commissioned; internally peer reviewed.  ...  are able, among others, to classify and predict mutations in lung and liver cancers, and to predict microsatellite instability in gastrointestinal cancer.  ... 
doi:10.1136/esmoopen-2020-001048 pmid:33037034 pmcid:PMC7549462 fatcat:a36jyjt42je4pasfrglyaq4dw4
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