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Measures of vascular reactivity: prognostic crystal ball or Pandora's box?
2008
Journal of applied physiology
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Although the goal to develop a simple, noninvasive test of vascular reactivity is laudable, much work remains to bring a "crystal ball" into clinical practice that will provide real prognostic value in ...
doi:10.1152/japplphysiol.90741.2008
pmid:18556427
fatcat:vh3vtg2ylffyvb6rsqo5d3qg5q
Development and initial evaluation of 7-T q-ball imaging of the human brain
2008
Magnetic Resonance Imaging
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Q-ball imaging (QBI) overcomes this limitation of DTI by more fully characterizing the angular dependence of intravoxel diffusion with larger numbers of diffusion-encoding directional measurements at higher ...
Using spherical harmonic reconstruction of the q-ball orientation distribution function at b=3000 s/mm 2 , 7T QBI allowed accurate visualization of crossing fiber tracts with fewer diffusion-encoding acquisitions ...
Both the 3T and the 7T scanners were equipped with gradient coil sets that have maximum amplitudes of 40 mT/m and maximum slew rates of 150 T/m/s. ...
doi:10.1016/j.mri.2007.05.011
pmid:17692489
pmcid:PMC2997615
fatcat:iny4bqugdfbubkg6te4mzyapjy
Restrained eating and memory specificity
2010
Appetite
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Chris Ball) not for publication 1-757-221 1760 (office); 1-757-221 3896 (fax) Restrained Eating and 2 Abstract Autobiographical memories are personal experiences that we store across our life-span. ...
., 2003; Laberg & Andersson, 2004; Nandrino, Doba, Annick, Christophe, & Pezard, 2006 ). ...
There was no difference in the number of specific memories retrieved by dieters (M = 5.8; SD = 1.3) when compared with non-dieters (M = 6.0; SD = 1.2), t(53) = 0.77, p>.05. ...
doi:10.1016/j.appet.2010.06.001
pmid:20540980
fatcat:gq62sm6cfbfz5piqytqkvt7quq
Measuring Conflict in a Multi-Source Environment as a Normal Measure
[article]
2018
arXiv
pre-print
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In a multi-source environment, each source has its own credibility. If there is no external knowledge about credibility then we can use the information provided by the sources to assess their credibility. In this paper, we propose a way to measure conflict in a multi-source environment as a normal measure. We examine our algorithm using three simulated examples of increasing conflict and one experimental example. The results demonstrate that the proposed measure can represent conflict in a
arXiv:1803.04556v1
fatcat:cqi7kxq5znffxdrx5jayiqjuza
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... ngful way similar to what a human might expect and from it we can identify conflict within our sources.
Standard PBMC cryopreservation selectively decreases detection of nine clinically-relevant T-cell markers
[article]
2021
bioRxiv
pre-print
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was reduced among at least one T-cell subset following standard processing, although the frequency of CD4, CD8 and regulatory T cells was unaffected. ...
Nevertheless, a six-month-long cryopreservation did not impair the expression levels of many other membrane and all the eight tested intracellular lineage or functional T-cell markers. ...
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doi:10.1101/2021.05.18.443634
fatcat:sxa5kir74vftjm6ykfz22sja6y
Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
[article]
2020
bioRxiv
pre-print
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Many players regulating the CD4+ T cell-mediated inflammatory response have already been identified. ...
genes encoding selenocysteine in humans, as a gene regulating the effector functions of human CD4 T cells. ...
, diluted in 5% BSA in PBS-T with 0.025% sodium azide. ...
doi:10.1101/2020.07.06.189456
fatcat:2cpskmllbbbcratveoqzxanihm
Fiber ball white matter modeling in focal epilepsy
2021
Human Brain Mapping
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Fiber ball imaging (FBI) and its extension fiber ball white matter modeling (FBWM) are such recently described multicompartment approaches. ...
Fiber ball white matter modeling (FBWM) significant differences between patients with refractory epilepsy, nonrefractory epilepsy and controls T A B L E 4 Parameters Tract Controls Refractory αFWE Min ...
There was no significant difference in age (t = 0.62, p = .54), age of onset of epilepsy (t = 0.02, p = .99) or duration of epilepsy (t = 0.71, p = .54) between refractory and nonrefractory patient groups ...
doi:10.1002/hbm.25382
pmid:33605514
pmcid:PMC8090772
fatcat:vnw2nppyybcprfqwjwsec555iq
DJ-1 depletion slows down immunoaging in T-cell compartments
[article]
2021
bioRxiv
pre-print
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However, the underlying molecular mechanisms, especially the genetic factors contributing to imbalance of naïve/memory T-cell subpopulations, still remain largely elusive. ...
gender-matched unaffected sibling carriers of similar ages, the index PD patient with DJ-1 deficiency showed a decline in many critical immunoaging features, including almost doubled frequencies of non-senescent T ...
cells, e.g., CD27 + CD28 + CD8 T cells (Fig. 1b ). ...
doi:10.1101/2021.05.21.445139
fatcat:jdlihkhpf5hyhng2deflq777zm
Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
2021
iScience
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Many players regulating the CD4+ T cell-mediated inflammatory response have already been identified. ...
However, the critical nodes that constitute the regulatory and signaling networks underlying CD4 T cell responses are still missing. ...
antibodies, diluted in 5% BSA in PBS-T with 0.025% sodium azide. ...
doi:10.1016/j.isci.2021.102289
pmid:33851102
pmcid:PMC8024663
fatcat:r7le6vg3ezgvlntucuvgj6jgmi
Asymptotic expected T-functionals of random polytopes with applications to L_p surface areas
[article]
2023
arXiv
pre-print
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An asymptotic formula is proved for the expected T-functional of the convex hull of independent and identically distributed random points sampled from the Euclidean unit sphere in ℝ^n according to an arbitrary ...
He obtained asymptotic formulas for the expected volume and expected surface area of a random polytope inscribed in a ball, and introduced what is known today as the T -functional T n,k a,b (Q) of a polytope ...
function on the Euclidean unit sphere or unit ball in R n . ...
arXiv:2202.01353v3
fatcat:guz3fdssxfahjfizid5e2wmfue
Not all streaks are the same: Individual differences in risk preferences during runs of gains and losses
2012
Judgment and Decision Making
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Consequently, the final bank amount for all participants (M =$10.06; SD = $0.84) did not vary significantly from the participant's starting bank of $10.00, t(59) = 0.58, p>.05. ...
doaj:015e659813984c9cbf2a9ebdeec1d4fc
fatcat:jwzvscsudbfpnkm7btz2jyivg4
Standard Peripheral Blood Mononuclear Cell Cryopreservation Selectively Decreases Detection of Nine Clinically Relevant T Cell Markers
2021
ImmunoHorizons
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, senescence, and other functions) was reduced among at least one T cell subset following standard processing, although the frequency of CD4, CD8, and regulatory T cells was unaffected. ...
Nevertheless, a 6-mo-long cryopreservation did not impair the percentages of cells expressing many other membrane and all the eight tested intracellular lineage or functional T cell markers. ...
fresh CD8 T cells. ...
doi:10.4049/immunohorizons.2100049
pmid:34433626
fatcat:tf2uj4r22bazbcr6rjntyfnzdi
A pilot trial of a videogame-based exercise program for methadone maintained patients
2014
Journal of Substance Abuse Treatment
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Few studies have examined exercise as a substance use disorder treatment. This pilot study investigated the feasibility and acceptability of an exercise intervention comprising the Wii Fit Plus ™ and of a time-and-attention sedentary control comprising Wii ™ videogames. We also explored their impact on physical activity levels, substance use, and psychological wellness. Twenty-nine methadone-maintained patients enrolled in an 8-week trial were randomly assigned to either Active Game Play (Wii
doi:10.1016/j.jsat.2014.05.007
pmid:25012555
pmcid:PMC4487635
fatcat:2kz75ayokfbr7jhfwcuvvfuzae
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... t Plus ™ videogames involving physical exertion) or Sedentary Game Play (Wii ™ videogames played while sitting). Participants had high satisfaction and study completion rates. Active Game Play participants reported greater physical activity outside the intervention than Sedentary Game Play participants despite no such differences at baseline. Substance use decreased and stress and optimism improved in both conditions. Active Game Play is a feasible and acceptable exercise intervention, and Sedentary Game Play is a promising timeand-attention control. Further investigations of these interventions are warranted.
Amorphism and Thermal Decomposition of Salicylsalicylic Acid—A Cautionary Tale
2016
Journal of Pharmaceutical Sciences
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J 7.7, H(11)), 7.39 (1 H, t, J 7.6, H(18)), 7.33 (1 H, d, J 8.1, H(9)), 7.17 (1 H, d, J
8.2, H(16)), 7.01 (1 H, d, J 8.5, H(2)), 6.95 (1 H, t, J 7.6, H ...
H (600 MHz, TCE-d 2 ) 8.33 (1 H, dd, J 7.8, 1.7, H(12)), 8.09 (2 H, m, H(5,19)), 7.73 (1 H,
td, J 7.8, 1.7, H(10)), 7.64 (1 H, td, J 7.8, 1.8, H(17)), 7.53 (1 H, td, J 7.7, 1.8, H(3)), 7.45
(1 H, t, ...
doi:10.1016/j.xphs.2016.06.009
pmid:27431013
fatcat:2zwway3pgbh2xay4bljykmddva
Novel Technique of Sampling the Urinary Bladder for Urothelial Carcinoma Specimens
2015
International Journal of Surgical Pathology
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Results Conclusions Urinary bladder (UB) sampling in radical cystectomy specimens usually involves taking three or more fullthickness strips of UB, oriented either randomly or in sagittal planes and including areas of interest. Pathological diagnostic information required for adequate clinical follow-up is often adequate; however, pathological assessment of the anatomical relationship of the urothelial carcinoma (UC) with the remaining UB is challenging. A new technique to map and sample the
doi:10.1177/1066896914567329
pmid:25627071
fatcat:hi3fhalalzcibkn53267zrs3qu
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... ire urinary bladder is proposed. It enables identification of the anatomical relationship of the tumor and remaining urinary bladder. Materials and Methods Fifty radical cystectomy specimens: •39 from men and 11 from women •9 for superficial UC and 41 for muscle invasive UC The grossing technique is as follows.
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