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Clinical Applications of Artificial Intelligence—An Updated Overview

Ștefan Busnatu, Adelina-Gabriela Niculescu, Alexandra Bolocan, George E. D. Petrescu, Dan Nicolae Păduraru, Iulian Năstasă, Mircea Lupușoru, Marius Geantă, Octavian Andronic, Alexandru Mihai Grumezescu, Henrique Martins
2022 Journal of Clinical Medicine  
Moreover, a diverse repertoire of methods can be chosen towards creating performant models for use in medical applications, ranging from disease prediction, diagnosis, and prognosis to opting for the most  ...  Artificial intelligence has the potential to revolutionize modern society in all its aspects.  ...  [86] independent of the images (for testing dataset) Automatic assessment and classification of the EmA test for celiac disease SVM 2597 high-quality IgA class Finland EmA images collected in 2017-2018  ... 
doi:10.3390/jcm11082265 pmid:35456357 pmcid:PMC9031863 fatcat:mtzdrc7nyzgbjeyou3h4cuso7a

The Future Role of Machine Learning in Clinical Transplantation

Katie L Connor, Eoin D O'Sullivan, Lorna P Marson, Stephen J Wigmore, Ewen M Harrison
2020 Transplantation  
The use of artificial intelligence and machine learning (ML) has revolutionised our daily lives and will soon be instrumental in healthcare delivery.  ...  review, we explore common approaches used in ML in solid organ clinical transplantation and consider opportunities for ML to help clinicians and patients.  ...  disease, and segmentation (eg, identification of organs) to assisting total kidney volume is a biomarker for disease progres- in complex classification (eg, grades of rejection).  ... 
doi:10.1097/tp.0000000000003424 pmid:32826798 fatcat:64kbnvm2tjgldptslpt7bhtgwi

The impact of artificial intelligence in medicine on the future role of the physician

Abhimanyu S. Ahuja
2019 PeerJ  
The practice of medicine is changing with the development of new Artificial Intelligence (AI) methods of machine learning.  ...  Coupled with rapid improvements in computer processing, these AI-based systems are already improving the accuracy and efficiency of diagnosis and treatment across various specializations.  ...  machines'' (Society for the Study of Artificial Intelligence and Simulation of Behavior, 2018) .  ... 
doi:10.7717/peerj.7702 pmid:31592346 pmcid:PMC6779111 fatcat:wcxq5smsfbarndj6kgxtssampe

SuperHistopath: A Deep Learning Pipeline for Mapping Tumor Heterogeneity on Low-Resolution Whole-Slide Digital Histopathology Images

Konstantinos Zormpas-Petridis, Rosa Noguera, Daniela Kolarevic Ivankovic, Ioannis Roxanis, Yann Jamin, Yinyin Yuan
2021 Frontiers in Oncology  
Finally, SuperHistopath is efficient for annotation of ground-truth datasets (as there is no need of boundary delineation), training and application (~5 min for classifying a whole-slide image and as low  ...  SuperHistopath efficiently combines i) a segmentation approach using the linear iterative clustering (SLIC) superpixels algorithm applied directly on the whole-slide images at low resolution (5x magnification  ...  The neuroblastoma preclinical dataset was built from H&E images collected during previous in vivo studies approved by The Institute of Cancer Research Animal Welfare and Ethical Review Body and performed  ... 
doi:10.3389/fonc.2020.586292 pmid:33552964 pmcid:PMC7855703 fatcat:clfhj3bqejevhdfzioxwayf77m

The Need for Alternatives to Liver Biopsies: Non-Invasive Analytics and Diagnostics

James Neuberger, Owen Cain
2021 Hepatic Medicine : Evidence and Research  
Many diseases of the liver can be diagnosed and managed using serological and radiological techniques; the degree of fibrosis and fat can often be assessed by serological or imaging techniques and the  ...  Histology remains essential for the diagnosis and management of many disorders affecting the liver.  ...  enhance the value of the liver biopsy in the coming years. 77, 78 Recent advances in slide scanners now allow the creation of "digital/virtual" slides that allow whole slide imaging (WSI) and additional  ... 
doi:10.2147/hmer.s278076 pmid:34163263 pmcid:PMC8214024 fatcat:ioo6ixgwo5c3pafrtsvwxbm2cm

Applications of discriminative and deep learning feature extraction methods for whole slide image analysis: A survey

Khaled Al-Thelaya, Nauman Ullah Gilal, Mahmood Alzubaidi, Fahad Majeed, Marco Agus, Jens Schneider, Mowafa Househ
2023 Journal of Pathology Informatics  
Digital pathology technologies, including whole slide imaging (WSI), have significantly improved modern clinical practices by facilitating storing, viewing, processing, and sharing digital scans of tissue  ...  Researchers have proposed various artificial intelligence (AI) solutions for digital pathology applications, such as automated image analysis, to extract diagnostic information from WSI for improving pathology  ...  Journal of Pathology Informatics 14 (2023) 100335 Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have  ... 
doi:10.1016/j.jpi.2023.100335 pmid:37928897 pmcid:PMC10622844 fatcat:mhk7i7a7dvegflinf6e27docp4

2021 Index IEEE Journal of Biomedical and Health Informatics Vol. 25

2021 IEEE journal of biomedical and health informatics  
The primary entry includes the coauthors' names, the title of the paper or other item, and its location, specified by the publication abbreviation, year, month, and inclusive pagination.  ...  Departments and other items may also be covered if they have been judged to have archival value. The Author Index contains the primary entry for each item, listed under the first author's name.  ...  ., +, JBHI Aug. 2021 3073-3081 Integration of CNN, CBMIR, and Visualization Techniques for Diagnosis and Quantification of Covid-19 Disease.  ... 
doi:10.1109/jbhi.2022.3140980 fatcat:ufig7b54gfftnj3mocspoqbzq4

Artificial Intelligence in Translational Medicine

Simone Brogi, Vincenzo Calderone
2021 International Journal of Translational Medicine  
As a consequence of the mentioned scenario, scientific vocabulary was enriched by novel lexicons such as machine learning (ML)/deep learning (DL) and overall artificial intelligence (AI).  ...  community to gain access to biological datasets, clinical data and several databases containing billions of pieces of information concerning scientific knowledge.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/ijtm1030016 fatcat:c6g6ld26gjg6jbkcddauo44qvu

Mass Spectrometry Imaging Spatial Tissue Analysis toward Personalized Medicine

Juliana P. L. Gonçalves, Christine Bollwein, Kristina Schwamborn
2022 Life  
Complementary information can be obtained from different omic approaches in combination with the traditional macro- and microscopic analysis of the tissue, providing a more complete assessment of the disease  ...  In the future, intercenter studies may provide the needed confirmation on the reproducibility, robustness, and applicability of the developed classification models for tissue characterization to assist  ...  Machine learning and artificial intelligence (AI) have generally been regarded as competition for human labor and perhaps knowledge for several decades.  ... 
doi:10.3390/life12071037 pmid:35888125 pmcid:PMC9318569 fatcat:qza72pdl6jdn3jvu5jrgnqmpgi

Diffusion-Weighted MRI in the Genitourinary System

Thomas De Perrot, Christine Sadjo Zoua, Carl G. Glessgen, Diomidis Botsikas, Lena Berchtold, Rares Salomir, Sophie De Seigneux, Harriet C. Thoeny, Jean-Paul Vallée
2022 Journal of Clinical Medicine  
The applications extend to whole-body imaging for both neoplastic and non-neoplastic diseases.  ...  One of the most promising developments of renal DWI is the estimation of renal fibrosis in chronic kidney disease (CKD) patients.  ...  In the kidney, the most promising applications of DWI may be the quantification of renal fibrosis and the prediction of disease evolution in CKD.  ... 
doi:10.3390/jcm11071921 pmid:35407528 pmcid:PMC9000195 fatcat:4j3uctnhibdjpeff7o2hlmzpkm

Systems biology and clinical cytomics: The 10th Leipziger workshop and the 3rd international workshop on slide-based cytometry

Attila Tárnok, Günther K. Valet, Frank Emmrich
2005 Cytometry Part A  
clinical importance for the assessment of systemic and organspecific autoimmune disease.  ...  Conclusion: We developed a whole blood assay to assess the effects of immunosuppressants on apoptosis.  ...  Aims: Development of triple fluorescent labeling method for leukocytes and application of SFM for their automated analysis and counting on peripheral blood specimen.  ... 
doi:10.1002/cyto.a.20204 pmid:16541487 fatcat:3tnq7rzlone57e33u7bqiafuxu

Applicability of lung ultrasound in COVID-19 diagnosis and evaluation of the disease progression: A systematic review

Andressa Oliveira Peixoto, Rafael Miranda Costa, Raísa Uzun, Andrea de Melo Alexandre Fraga, José Dirceu Ribeiro, Fernando Augusto Lima Marson
2021 Pulmonology  
With the increase in the number of studies and the use of ultrasound scans, LU has been shown as a useful tool to evaluate progression, therapeutic response and follow-up of pulmonary disease in the patients  ...  One of the limitations to the management of the COVID-19 is the diagnostic imaging to evaluate lung impairment and the patients' clinical evolution, mainly, in more severe cases that require admission  ...  Acknowledgments The authors are grateful to the professionals in the teams of the referenced pediatric urgency and emergency and pediatric pulmonology units as well as to the University of Campinas radiology  ... 
doi:10.1016/j.pulmoe.2021.02.004 pmid:33931378 pmcid:PMC7983424 fatcat:vnrwnfpvlbc7tdwxij3uelchgu

PATHOBIOLOGY AND EMERGING TECHNIQUES

2023 Laboratory Investigation  
Counting Ki67 labeling index, a requirement for PanNET diagnosis and management, continues to be challenging.  ...  The same observers were asked to divide the same image into a grid of 9 boxes and select the most and least positiveappearing 2 boxes and took their average as the final Ki67. 3) AI method.  ...  Comparative Analysis of c-MET Expression Using Image Analysis Model in IHC Stained WSIs Hyeon Seok Yang 1 , Yunseob Hwang 1 , Yoon-La (Yuna) Choi 2 , Kyungsoo Jung 3 , Minjung Sung 3 , Young Kee Shin 4  ... 
doi:10.1016/j.labinv.2023.100098 fatcat:k6c6u72cbjfzbow6rwfbtvfmb4

Deep learning in medical imaging and radiation therapy

Berkman Sahiner, Aria Pezeshk, Lubomir M. Hadjiiski, Xiaosong Wang, Karen Drukker, Kenny H. Cha, Ronald M. Summers, Maryellen L. Giger
2018 Medical Physics (Lancaster)  
We introduce the general principles of DL and convolutional neural networks, survey five major areas of application of DL in medical imaging and radiation therapy, identify common themes, discuss methods  ...  The goals of this review paper on deep learning (DL) in medical imaging and radiation therapy are to (a) summarize what has been achieved to date; (b) identify common and unique challenges, and strategies  ...  INTRODUCTION In the last few years, artificial intelligence (AI) has been rapidly expanding and permeating both industry and academia. 2] [3] Every week, there is a news story about an AI system that  ... 
doi:10.1002/mp.13264 pmid:30367497 pmcid:PMC9560030 fatcat:bottst5mvrbkfedbuocbrstcnm

LIVER PATHOLOGY

2024 Laboratory Investigation  
Ultimately, AMR diagnosis must rely on a multimodal "gold standard" combining clinical, DSA, histopathologic, C4d staining, and other factors.  ...  C4d immunohistochemistry (IHC) is used as a marker of AMR; however, the performance characteristics of C4d are not always fully characterized.  ...  Whole slide images (WSI) of H&E-stained slides from formalin-fixed, paraffin-embedded tissue were obtained using a spectrum of WSI scanners.  ... 
doi:10.1016/j.labinv.2024.101663 fatcat:bn77hpcquzamthj7dee6jvti2m
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