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Multi-Channel Front-End for Electrochemical Sensing of Metabolites, Drugs, and Electrolytes

Ivan Ny Hanitra, Francesca Criscuolo, Nadezda Pankratova, Sandro Carrara, Giovanni De Micheli
2019 IEEE Sensors Journal  
A multi-channel front-end for electrochemical sensing is presented. It consists of a multiplexed four-channel readout interface supporting amperometric, voltammetric, and potentiometric measurements.  ...  The programmability, versatility and portability of the front-end interface paves the way for a continuous monitoring of different families of biomarkers, suitable for advanced healthcare diagnosis and  ...  CIRCUIT ARCHITECTURE In this section, the analog front-end circuitry for amperometric and potentiometric measurements are described. A.  ... 
doi:10.1109/jsen.2019.2959885 fatcat:5o4zhymwxnd7vac62lzpoyq44y

Construction and analytical applications of a palm-sized microcontroller-based amperometric analyzer

Elias M. Avdikos, Mamas I. Prodromidis, Constantinos E. Efstathiou
2005 Sensors and actuators. B, Chemical  
The use of a microcontroller combined with analog and digital supporting circuits allows: (i) generation of the applied potential and the acquisition of analog signals with a gain auto-scaling capability  ...  The design and development of a palm-sized (9 cm × 11 cm × 3 cm), cost-effective, microcontroller-operated analyzer for direct amperometric measurements is described.  ...  For achieving the highest possible precision over a wide dynamic range of i CELL -values the analyzer is equipped with the capability of auto-scaling, i.e. the software through the analog multiplexer S  ... 
doi:10.1016/j.snb.2004.10.029 fatcat:xqsd3lvvn5depl3gnas4oiywpa

CMOS Analog Front-End IC for Gas Sensors

Hyuntae Kim, Bertan Bakkaloglu
2011 Additional Conferences (Device Packaging, HiTEC, HiTEN, & CICMT)  
This thesis presents a gas sensor readout IC for amperometric and conductometric electrochemical sensors.  ...  The Analog Front-End (AFE) readout circuit enables tracking long term exposure to hazardous gas fumes in diesel and gasoline equipments, which may be correlated to diseases.  ...  Figure 6 . 1 61 Micrograph of the analog front end IC for gas sensor system.  ... 
doi:10.4071/2011dpc-wp25 fatcat:k6lqrnkh3rhmdklep3w2qa3ioe

KickStat: A Coin-Sized Potentiostat for High-Resolution Electrochemical Analysis

Orlando S. Hoilett, Jenna F. Walker, Bethany M. Balash, Nicholas J. Jaras, Sriram Boppana, Jacqueline C. Linnes
2020 Sensors  
The demand for wearable and point-of-care devices has led to an increase in electrochemical sensor development to measure an ever-increasing array of biological molecules.  ...  We measured the faradaic current of an anti-cocaine aptamer using cyclic voltammetry and square wave voltammetry and demonstrated that KickStat's response was within 0.6% of a high-end benchtop potentiostat  ...  Acknowledgments: We would like to thank Peter Kissinger, Frédérique Deiss, Netz Arroyo, Rebecca Lai, and Kevin Plaxco for their advice on electrochemistry techniques.  ... 
doi:10.3390/s20082407 pmid:32340294 fatcat:bzedn5hoindsxbju73nm3lkgsu

Portable Bio-Devices: Design of electrochemical instruments from miniaturized to implantable devices [chapter]

Jordi Colomer-Farrarons, Pere Ll., A. Ivon, Josep Samitier
2011 New Perspectives in Biosensors Technology and Applications  
Proposed generic implantable front-end architecture.Fig. 20.  ...  for amperometric chemical sensors for a Glucose Meter Application.  ...  Miribel-Catala, A. Ivoń Rodriǵuez-Villarreal and Josep Samitier (2011) .  ... 
doi:10.5772/17212 fatcat:ydwxqmix7nbtpfllba5ndz3ecy

Wireless Integrated Biosensors for Point-of-Care Diagnostic Applications

Ebrahim Ghafar-Zadeh
2015 Sensors  
In this review paper, we examine three major categories of miniaturized integrated devices, namely; the implantable Wireless Bio-Sensors (WBSs), the wearable WBSs and the handheld WBSs.  ...  Recent advances in integrated biosensors, wireless communication and power harvesting techniques are enticing researchers into spawning a new breed of point-of-care (POC) diagnostic devices that have attracted  ...  Acknowledgments The author would like to thank NSERC Canada for support. The author would also like to acknowledge the proofreading and editing of M. Amara.  ... 
doi:10.3390/s150203236 pmid:25648709 pmcid:PMC4367357 fatcat:p22oxy5jhfcjhgbpg2kl7jgucu

How to Assess the Measurement Performance of Mobile/Wearable Point-of-Care Testing Devices? A Systematic Review Addressing Sweat Analysis

Sarah Tonello, Giulia Abate, Michela Borghetti, Nicola Francesco Lopomo, Mauro Serpelloni, Emilio Sardini
2022 Electronics  
Recent advances in technologies for biosensor integration in mobile or wearable devices have highlighted the need for the definition of proper validation procedures and technical standards that enable  ...  Thus, reliable assessment—in terms of limits of detection/quantitation, linearity, range, analytical and diagnostic sensitivity/specificity, accuracy, repeatability, reproducibility, cross-reactivity,  ...  • A DC-DC converter (or low-dropout voltage regulator, etc.) to realize regulated and stable voltage from one single power supply and suitable for all the electronic sections-the analog front end and  ... 
doi:10.3390/electronics11050761 fatcat:yqz4r6buzzewrkvuaepxhrhv2a

Microfabrication techniques for chemical/biosensors

A. Hierlemann, O. Brand, C. Hagleitner, H. Baltes
2003 Proceedings of the IEEE  
Microfabrication processes for chemical and biochemical sensors are reviewed.  ...  Fundamental chemical sensor principles are briefly abstracted and corresponding state-of-the-art examples of microfabricated chemical sensors and biosensors are given.  ...  CMOS Integrated Voltammetric/Amperometric Sensor Two different electrode configurations are commonly used for voltammetric/amperometric measurements.  ... 
doi:10.1109/jproc.2003.813583 fatcat:oezy7icqjja4xgi6jg2v7dwkz4

Wearable sweat sensors

Mallika Bariya, Hnin Yin Yin Nyein, Ali Javey
2018 Nature Electronics  
Various physical and chemical sensors will need to be integrated to obtain a complete picture of dynamic health.  ...  Ions including Ca 2+ and K + are present in the mM range.  ...  Acknowledgements The authors acknowledge support from the National Science Foundation (NSF), Berkeley Sensor and Actuator Center (BSAC), NSF Nanomanufacturing Systems for Mobile Computing and Mobile Energy  ... 
doi:10.1038/s41928-018-0043-y fatcat:lllldc2spretfpxyf53japh3v4

Genosensor on gold films with enzymatic electrochemical detection of a SARS virus sequence☆

Patricia Abad-Valle, M. Teresa Fernández-Abedul, Agustín Costa-García
2005 Biosensors & bioelectronics  
The use of a sensitive electrochemical technique such as square wave voltammetry allowed a detection limit of 6 pM to be obtained for this DNA sequence, lower than any other found in the bibliography.  ...  A complementary strand (probe), labelled with a thiol group at the 3'-end, was immobilised on the film.  ...  Detection limit and linear dynamic range With the optimised parameters, calibration curves were performed for IC and ␣-naphthol.  ... 
doi:10.1016/j.bios.2004.10.019 pmid:15797323 pmcid:PMC7126974 fatcat:y3mxozab4vhgvntdutjffdod2u

A Bidirectional-Current CMOS Potentiostat for Fast-Scan Cyclic Voltammetry Detector Arrays

2018 IEEE Transactions on Biomedical Circuits and Systems  
He is currently also with ExoCytronics LLC, Columbia, MO, where he is working on data acquisition hardware and software for electrochemical sensor arrays.  ...  , and high-throughput drug screening.  ...  His research interests include low-power analog, mixed-signal, and RF integrated circuit design.  ... 
doi:10.1109/tbcas.2018.2828828 pmid:29994774 pmcid:PMC6131114 fatcat:gq7f45eojvanzizzj4oukp5j3q

70 years of bilirubin sensing: towards the point-of-care bilirubin monitoring in cirrhosis and hyperbilirubinemia

Jean Pierre Ndabakuranye, Shiqiang Li, Genia Burchall, Kate Fox, Terrence Piva, Zhangyu Xu, Omid Kavehei, Steven Prawer, Arman Ahnood
2022 Sensors & Diagnostics  
Bilirubin is clinically confirmed as a biomarker for liver health and has been utilized to implement the prognostic systems for cirrhosis and hyperbilirubinemia.  ...  Optical and chemical methods have been developed...  ...  It incorporates a light sensor system (LEDs, a photodiode, and probes), analog front end (AFE), Analog -to -Digital Converter (ADC), an MCU and a display system.  ... 
doi:10.1039/d2sd00033d fatcat:iukkx2e2lbed5iewy6r5bfw56u

Development of a computer controlled multichannel potentiostat for applications with flowing solution analysis

Tang Fang, Michael McGrath, Dermot Diamond, Malcolm R. Smyth
1995 Analytica Chimica Acta  
Control o f the purpose built instrumentation was effected with a 486-33 personal computer and Analog D evices RTI-815 and RTI-817 data acquisition/control cards, which are responsible for hardware control  ...  ic and technical o f the School o f C hem ical Sciences, D ublm City U niversity, for their valuable assistance durmg m y stay m Ireland I w ould like to thank D octor Peter Filelden for the donation  ...  or other analogue output o f an instrument or sensor to a binary form that can be handled by the digital computer ADC's are characterised by their resolution, dynamic range, and maximum through-put The  ... 
doi:10.1016/0003-2670(94)00482-2 fatcat:h4q2syipr5fmpgts2uzhv46wti

Recent Progress in Rapid Determination of Mycotoxins Based on Emerging Biorecognition Molecules: A Review

Yanru Wang, Cui Zhang, Jianlong Wang, Dietmar Knopp
2022 Toxins  
and high-throughput multiplexing, and determination of masked mycotoxins, including stereoisomeric degradation products.  ...  There is an urgent demand for new low-cost, easy-to-use, and portable analytical devices for rapid on-site determination.  ...  This sensor possessed excellent performance, with an LOD of 0.66 pM for PAT and a logarithmic linear range from 0.001 to 100 nM.  ... 
doi:10.3390/toxins14020073 pmid:35202100 pmcid:PMC8874725 fatcat:bco5t4fugbektnuis3peuph7iu

2020 Index IEEE Transactions on Instrumentation and Measurement Vol. 69

2020 IEEE Transactions on Instrumentation and Measurement  
Converter Using All-Digital Nested Delay-Locked Loops With 50-ps Resolution and High Throughput for LiDAR TIM Nov. 2020 9262-9271 Helsen, J., see Huchel, L., TIM July 2020 4145-4153 Hemavathi, N.,  ...  Oct. 2020 7530-7541 Hernandez, A., see Aparicio-Esteve, E., TIM Aug. 2020 5589-5603 Hernandez, H., de Souza Sanches, B.C., Carvalho, D., Bregant, M  ...  ., +, TIM May 2020 2208-2217 A Compact Low-Power Current-to-Digital Readout Circuit for Amperometric Electrochemical Sensors.  ... 
doi:10.1109/tim.2020.3042348 fatcat:a5f4fsqs45fbbetre6zwsg3dly
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