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FastSurfer-HypVINN: Automated sub-segmentation of the hypothalamus and adjacent structures on high-resolutional brain MRI [article]

Santiago Estrada, David Kügler, Emad Bahrami, Peng Xu, Dilshad Mousa, Monique M.B. Breteler, N. Ahmad Aziz, Martin Reuter
2023 arXiv   pre-print
While the only previous attempt to automatically sub-segment the hypothalamus with a neural network showed promise for 1.0 mm isotropic T1-weighted (T1w) MRI, there is a need for an automated tool to sub-segment  ...  We, therefore, introduce a novel, fast, and fully automated deep learning method named HypVINN for sub-segmentation of the hypothalamus and adjacent structures on 0.8 mm isotropic T1w and T2w brain MR  ...  These multi-modal protocols recommend segmenting the hypothalamus using simultaneous visualization of registered T1-weighted (T1w) and T2-weighted (T2w) MR images.  ... 
arXiv:2308.12736v1 fatcat:llxmpqyowzcmbd7ly42pku4cny

Development and Evaluation of an Algorithm for the Computer-Assisted Segmentation of the Human Hypothalamus on 7-Tesla Magnetic Resonance Images

Stephanie Schindler, Peter Schönknecht, Laura Schmidt, Alfred Anwander, Maria Strauß, Robert Trampel, Pierre-Louis Bazin, Harald E. Möller, Ulrich Hegerl, Robert Turner, Stefan Geyer, Wang Zhan
2013 PLoS ONE  
We present a computer-assisted algorithm for the manual segmentation of the human hypothalamus using T1-weighted 7T magnetic resonance imaging.  ...  A detailed segmentation algorithm (unilateral hypothalamus) was developed for colour-coded, histogram-matched images, and evaluated in a sample of 10 subjects.  ...  [23] , we have developed a detailed segmentation algorithm for the hypothalamus on 7T MR images.  ... 
doi:10.1371/journal.pone.0066394 pmid:23935821 pmcid:PMC3720799 fatcat:pkg5dv57dvew3l4yxmejwtupju

Hypothalamus enlargement in mood disorders

S. Schindler, L. Schmidt, M. Stroske, M. Storch, A. Anwander, R. Trampel, M. Strauß, U. Hegerl, S. Geyer, P. Schönknecht
2018 Acta Psychiatrica Scandinavica  
Focus When the setting sun can't shine, The broken moon won't glow, And in a lone ant's shadow Myriads more long gone Vie for glory on and on Step out, Son of Man, breathe in.  ...  In vivo Strukturveränderungen des Hypothalamus bei uni-und bipolaren affektiven Störungen Als Kopf der Hypothalamus-Hypophysen-Nebennierenrinden-Achse spielt der Hypothalamus eine Schlüsselrolle für die  ...  Acknowledgements We are most grateful to Professor Ulrich Hegerl for stimulating discussions and for his longstanding support.  ... 
doi:10.1111/acps.12958 pmid:30229855 fatcat:tttmtyclcrazxho2gklyabnhgq

Multi-Coil MRI Reconstruction Challenge – Assessing Brain MRI Reconstruction Models and their Generalizability to Varying Coil Configurations [article]

Youssef Beauferris, Jonas Teuwen, Dimitrios Karkalousos, Nikita Moriakov, Mattha Caan, George Yiasemis, Lívia Rodrigues, Alexandre Lopes, Hélio Pedrini, Letícia Rittner, Maik Dannecker, Viktor Studenyak (+11 others)
2021 arXiv   pre-print
The Multi-Coil Magnetic Resonance Image (MC-MRI) Reconstruction Challenge provides a benchmark that aims at addressing these issues, using a large dataset of high-resolution, three-dimensional, T1-weighted  ...  The challenge has two primary goals: 1) to compare different MRI reconstruction models on this dataset and 2) to assess the generalizability of these models to data acquired with a different number of  ...  The organizers of the challenge also acknowledge Nvidia for providing a Titan V graphics processing unit and Amazon Web Services for providing computational infra-structure that was used by some of the  ... 
arXiv:2011.07952v2 fatcat:t55wnasrpveuzio2kfne756fhq

A practical Alzheimer's disease classifier via brain imaging-based deep learning on 85,721 samples

Bin Lu, Hui-Xian Li, Zhi-Kai Chang, Le Li, Ning-Xuan Chen, Zhi-Chen Zhu, Hui-Xia Zhou, Xue-Ying Li, Yu-Wei Wang, Shi-Xian Cui, Zhao-Yu Deng, Zhen Fan (+5 others)
2022 Journal of Big Data  
The sex classifier achieved 94.9% accuracy and served as a base model in transfer learning for the objective diagnosis of AD.  ...  Therefore, we built a practical brain MRI-based AD diagnostic classifier using deep learning/transfer learning on a dataset of unprecedented size and diversity.  ...  All 50,876 participants (contributing 85,721 samples) had at least one session with a T1-weighted structural brain image and information on their sex and age.  ... 
doi:10.1186/s40537-022-00650-y fatcat:t3jkxmdrwjhtzk2zknamqe2mre

Manually segmented template library for 8-year-old pediatric brain MRI data with 16 subcortical structures

Amanmeet Garg, Darren Wong, Karteek Popuri, Kenneth J. Poskitt, Kevin Fitzpatrick, Bruce Bjornson, Ruth E. Grunau, Mirza Faisal Beg
2014 Journal of Medical Imaging  
A manually delineated pediatric template library such as the one described here could provide a useful benchmark for testing segmentation algorithms.  ...  labels onto the unlabeled MRI images.  ...  R01 HD039783 to R.E.G., We would like to thank Ivan Cepeda and Gisela Gosse for recruitment and data collection, staff of the B.C.  ... 
doi:10.1117/1.jmi.1.3.034502 pmid:26158067 pmcid:PMC4478774 fatcat:zfn6ycecufazbfcak5ce462bbq

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy

Andri C. Tziortzi, Graham E. Searle, Sofia Tzimopoulou, Cristian Salinas, John D. Beaver, Mark Jenkinson, Marc Laruelle, Eugenii A. Rabiner, Roger N. Gunn
2011 NeuroImage  
We present a set of anatomical guidelines for the delineation of D3 relevant ROIs including substantia nigra, hypothalamus, ventral pallidum/substantia innominata, ventral striatum, globus pallidus and  ...  Keywords: dopamine D3 receptors PET PHNO region of interest ROI ventral striatum VST ventral pallidum hypothalamus extended amygdala [ 11 C]-(+)-PHNO is a D3 preferring PET radioligand which has recently  ...  Acknowledgments The authors would like to acknowledge Charalampos Tsoumpas, Paul Shotbolt, Christopher Long, Qi Guo, and Vincent Cunningham for useful discussions and Robert Comley for his role in acquisition  ... 
doi:10.1016/j.neuroimage.2010.06.044 pmid:20600980 fatcat:pc7wpu4r2vhlrc3mo5dc6a2rd4

Consistent cortical reconstruction and multi-atlas brain segmentation

Yuankai Huo, Andrew J. Plassard, Aaron Carass, Susan M. Resnick, Dzung L. Pham, Jerry L. Prince, Bennett A. Landman
2016 NeuroImage  
Finally, 200 MR volumetric images from an older adult sample are used to assess the robustness of MaCRUISE and FreeSurfer.  ...  Whole brain segmentation and cortical surface reconstruction are two essential techniques for investigating the human brain.  ...  This study was also supported by NIH 5R01NS056307, 5R21NS082891 and in part using the resources of the Advanced Computing Center for Research and Education  ... 
doi:10.1016/j.neuroimage.2016.05.030 pmid:27184203 pmcid:PMC4927397 fatcat:aagizrwmujaktlmfkp7atpou2i

Imaging characteristics of H3 K27M histone-mutant diffuse midline glioma in teenagers and adults

Stefanie Thust, Caroline Micallef, Sachi Okuchi, Sebastian Brandner, Atul Kumar, Kshitij Mankad, Stephen Wastling, Laura Mancini, Hans Rolf Jäger, Ananth Shankar
2021 Quantitative Imaging in Medicine and Surgery  
To assess anatomical and quantitative diffusion-weighted MR imaging features in a recently classified lethal neoplasm, H3 K27M histone-mutant diffuse midline glioma [World Health Organization (WHO) IV]  ...  The structural MR imaging findings varied between individuals and within tumours, often featuring signal heterogeneity on all MR sequences.  ...  and ATRX, and Ki67 on a Roche Ventana benchmark platform (21) (22) (23) .  ... 
doi:10.21037/qims-19-954 pmid:33392010 pmcid:PMC7719951 fatcat:6w4mgavvz5hova7pt52qxdnhh4

A Novel Receive-Only Liquid Nitrogen ($\hbox{LN}_{2}$ )-Cooled RF Coil for High-Resolution In Vivo Imaging on a 3-Tesla Whole-Body Scanner

Bobo Hu, Gopal Varma, Chris Randell, Stephen F. Keevil, Tobias Schaeffter, Paul Glover
2012 IEEE Transactions on Instrumentation and Measurement  
Abstract: The design and operation of a receive-only liquid nitrogen (LN 2 ) cooled coil and cryostat suitable for medical image on 3T whole body MR scanner is presented.  ...  Paul (2012) A novel receive-only liquid nitrogen (LN2)cooled RF coil for high-resolution in vivo imaging on a 3-Tesla whole-body scanner.  ...  For the MR image experiments, micron scale high resolution MR images of small animal were obtained on a clinical whole body scanner by using this engineering solution.  ... 
doi:10.1109/tim.2011.2157575 fatcat:xivpidaalrdxlfh6xk7nw6usca

What is new in computer vision and artificial intelligence in medical image analysis applications

Jimena Olveres, Germán González, Fabian Torres, José Carlos Moreno-Tagle, Erik Carbajal-Degante, Alejandro Valencia-Rodríguez, Nahum Méndez-Sánchez, Boris Escalante-Ramírez
2021 Quantitative Imaging in Medicine and Surgery  
We show how both areas have resulted in a large variety of methods that range from enhancement, detection, segmentation and characterizations of anatomical structures and lesions to complete systems that  ...  However, these imaging modalities also impose important limitations to the design of automatic image analysis systems for diagnosis aid due to their inherent characteristics such as signal to noise ratio  ...  (90) which provides a set of algorithms to segment the whole brain from T1-weighted images.  ... 
doi:10.21037/qims-20-1151 fatcat:mgzndm34bfcofdngnrzdvw5kyq

A - Postgraduate Educational Programme

2010 Insights into Imaging  
A S39 C B D E F G The majority of metastases are bright on T2-weighted and iso-or hypo-intense in liver on T1-weighted MR images. Desmoplastic reaction may render a metastasis dark at MRI.  ...  resulting in a homogeneous high-signal intensity on heavily T1-weighted 3D gradient echo images.  ...  Diffusion-weighted MR sequences can also help for that purpose.  ... 
doi:10.1007/s13244-010-0010-2 pmid:23099630 pmcid:PMC3534349 fatcat:5fiszmj5unftrhizcn3encksgy

Postgraduate Educational Programme

2008 European Radiology Supplements  
A S39 C B D E F G The majority of metastases are bright on T2-weighted and iso-or hypo-intense in liver on T1-weighted MR images. Desmoplastic reaction may render a metastasis dark at MRI.  ...  resulting in a homogeneous high-signal intensity on heavily T1-weighted 3D gradient echo images.  ...  Diffusion-weighted MR sequences can also help for that purpose.  ... 
doi:10.1007/s10406-008-0001-2 fatcat:gzbh2ky3enhabmfr7tz42qqqwi

Postgraduate Educational Programme

2009 European Radiology  
A S39 C B D E F G The majority of metastases are bright on T2-weighted and iso-or hypo-intense in liver on T1-weighted MR images. Desmoplastic reaction may render a metastasis dark at MRI.  ...  resulting in a homogeneous high-signal intensity on heavily T1-weighted 3D gradient echo images.  ...  Diffusion-weighted MR sequences can also help for that purpose.  ... 
doi:10.1007/s00330-009-1374-x pmid:19288110 fatcat:blzt6eohybeqjngnpyzlw7un6a

A postgraduate educational programme

2002 European Radiology  
A S39 C B D E F G The majority of metastases are bright on T2-weighted and iso-or hypo-intense in liver on T1-weighted MR images. Desmoplastic reaction may render a metastasis dark at MRI.  ...  resulting in a homogeneous high-signal intensity on heavily T1-weighted 3D gradient echo images.  ...  Diffusion-weighted MR sequences can also help for that purpose.  ... 
doi:10.1007/s00330-002-0001-x fatcat:swpi4r6hzrgozpfxwqgz55bmvi
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