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Article
Open AccessLong-term safety and tolerability of ambrisentan treatment for pediatric patients with pulmonary arterial hypertension: An open-label extension study
This open-label, extension study assessed long-term safety, tolerability, and efficacy of ambrisentan in a pediatric population (age 8– < 18 years) with pulmonary arterial hypertension (PAH). Following complet...
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Article
Open AccessSynthesizing differentially private location traces including co-locations
Privacy-preserving location synthesizers have been widely studied to perform private geo-data analysis. They have also been used for generating datasets for research or competitions. However, existing location...
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Article
Trans-subclavian approach for Impella CP implantation using the chimney graft in a pediatric patient with fulminant myocarditis during extracorporeal support
Impella is a device effective for the treatment of cardiogenic shock. However, among small children, its application has limitations due to left ventricle size and vasculature and the turning diameter of the a...
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Article
Open AccessQuantitative estimation of phospholipid molecules desorbed from a microbubble surface under ultrasound irradiation
Microbubbles have potential applications as drug and gene carriers, and drug release can be triggered by externally applied ultrasound irradiation while inside blood vessels. Desorption of molecules forming th...
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Chapter and Conference Paper
Synthesizing Privacy-Preserving Location Traces Including Co-locations
Location traces are useful for various types of geo-data analysis tasks, and synthesizing location traces is a promising approach to geo-data analysis while protecting user privacy. However, existing location ...
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Article
Pediatric patient with restrictive cardiomyopathy on staged biventricular assist device support with Berlin Heart EXCOR® underwent heart transplantation successfully: the first case in Japan
Pure restrictive cardiomyopathy is a strong risk factor for poor outcomes in children with cardiomyopathy on ventricular assist devices. Owing to concomitant right heart failure, children with end-staged restr...
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Article
Open AccessInnovative therapeutic strategy using prostaglandin I2 agonist (ONO1301) combined with nano drug delivery system for pulmonary arterial hypertension
Clinical outcomes of pulmonary arterial hypertension (PAH) may be improved using targeted delivery system. We investigated the efficacy of ONO1301 (prostacyclin agonist) nanospheres (ONONS) in Sugen5416/hypoxi...
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Chapter and Conference Paper
Understanding the Impact of Service Trials on Privacy Disclosure
We have many opportunities to disclose privacy information in exchange for convenient services. In the context of privacy calculus, numerous research studies have been conducted to date on the relation between...